Evidence map›Paper›PMID 20049465›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2010

Diagnostic superiority of a combined assessment of the systolic and early diastolic mitral annular velocities by tissue Doppler imaging for the differentiation of restrictive cardiomyopathy from constrictive pericarditis.

Thomas Butz, C Piper, C Langer, M Wiemer, T Kottmann, A Meissner, G Plehn, H J Trappe, D Horstkotte, L Faber

Abstract readComparative StudyControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.Clinical research in cardiology : official journal of the German Cardiac Society · 2012
    Trial
  3. Review
  4. Review
  5. Review
  6. Fast assessment of long axis strain with standard cardiovascular magnetic resonance: a validation study of a novel parameter with reference values.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2015
    Article
  7. Echocardiography signs of early cardiac impairment in patients with breast cancer and trastuzumab therapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2012
    Article
  8. Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus.Clinical research in cardiology : official journal of the German Cardiac Society · 2012
    Article
  9. Assessment of left ventricular diastolic function in children after successful repair of aortic coarctation.Clinical research in cardiology : official journal of the German Cardiac Society · 2011
    Article
  10. The relative atrial volume ratio and late gadolinium enhancement provide additive information to differentiate constrictive pericarditis from restrictive cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Thomas ButzDepartment of Cardiology, Heart Center Northern-Westphalia, Ruhr-University Bochum, Bad Oeynhausen, Germany. Thomas.Butz@Marienhospital-Herne.de
C Piper
C Langer
M Wiemer
T Kottmann
A Meissner
G Plehn
H J Trappe
D Horstkotte
L Faber
Heart and Diabetes Center North Rhine-Westphalia · DEUniversitätsklinik Marien Hospital Herne · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEchocardiographic tissue Doppler imaging (TDI) has been proposed as diagnostic tool for the differentiation between constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). The aim of this study was a comprehensive TDI analysis of systolic (S') and early diastolic (E') velocities of the septal and lateral mitral annulus (MA) in patients (pts) with severe diastolic dysfunction caused either by CP or RCM. METHODS AND

resultsSixty consecutive pts (34 men, mean age 61 +/- 11 years), 34 pts with proven CP and 26 pts with RCM due to cardiac amyloidosis, were included in the study. Forty-two of the 60 pts were in NYHA class III (70%). In pts with RCM systolic longitudinal velocity (S') was significantly decreased when compared to CP (septal MA 4.1 +/- 1.5 vs. 7.3 +/- 2.1 cm/s, p < 0.001; lateral MA 4.3 +/- 1.9 vs. 7.0 +/- 1.9 cm/s, p < 0.001). In addition, the RCM group showed a significantly decreased early diastolic longitudinal velocity (E'), both on the septal (4.1 +/- 1.6 vs. 12.9 +/- 4.9 cm/s, p < 0.001) and lateral side (4.8 +/- 1.9 vs. 11.3 +/- 3.7 cm/s; p < 0.001) of the mitral annulus. ROC analysis demonstrated an area under the curve of 0.889 (S' septal), 0.823 (S' lateral), 0.974 (E' septal), and 0.915 (E' lateral) for the differentiation of RCM and CP with a cutoff value of <8 cm/s. The combined use of an averaged S' cutoff value <8 cm/s as well as an E' cutoff value <8 at the lateral and septal MA demonstrated 93% sensitivity and 88% specificity for the diagnosis of RCM.

conclusionTDI provides a diagnostic superiority and an accurate discrimination between RCM and CP by using the combined cutoff value of <8 cm/s for S' and E' at both sides of the MA.

Indexed as

AgedCardiomyopathy, RestrictiveDiagnosis, DifferentialEchocardiography, DopplerFemaleHumansMaleMiddle AgedMitral ValvePericarditis, ConstrictiveSensitivity and Specificity

Identifiers

PMID20049465
OpenAlexW2082866962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.