ArticleRheumatology international2011
Health-related quality of life and its associations with mood condition in familial Mediterranean fever patients.
Article in Rheumatology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Results of the systematic literature search as basis for the "Evidence-based treatment recommendations for familial Mediterranean fever patients with insufficient response or intolerability to colchicine" of the Society for Pediatric and Adolescent Rheumatology and the German Society for Rheumatology].Zeitschrift fur Rheumatologie · 2020Pooled it
- The effect of rilonacept versus placebo on health-related quality of life in patients with poorly controlled familial Mediterranean fever.BioMed research international · 2014Trial
- Attack-Related Anticipatory Anxiety Symptoms in Familial Mediterranean Fever: An Exploratory Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Colchicine-Tolerant vs. Resistant Familial Mediterranean Fever: Comparative Analysis of Clinical, Psychosocial Characteristics and Quality of Life.Journal of clinical medicine · 2026Article
- The effects of self-efficacy in managing the disease and disease adaptation levels of Familial Mediterranean Fever (fmf) patients on satisfaction with life: a web-based cross-sectional study.Orphanet journal of rare diseases · 2025Observational
- Mental Ill-Health in young people with systemic autoinflammatory disease - a scoping review.Rheumatology international · 2025Article
- The efficacy of a single-dose anakinra injection during disease attack in pediatric familial Mediterranean fever.Rheumatology international · 2024Article
- Article
- Well-being in chronic pediatric inflammatory rheumatic diseases: the experience of a French healthcare network.Orphanet journal of rare diseases · 2023Article
- Clinical features, functional status, and quality of life in patients with late-onset familial Mediterranean fever.Northern clinics of Istanbul · 2023Article
- Factors affecting patient-acceptable symptom states and treatment decision in familial Mediterranean fever.Turkish journal of medical sciences · 2022Article
- Decreased exercise capacity, strength, physical activity level and quality of life in adult patients with familial Mediterranean feverTurkish journal of medical sciences · 2021Article
- Familial Mediterranean fever: Health-related quality of life and associated variables in a national cohort.Archives of rheumatology · 2021Article
- Real-Life Indications of Interleukin-1 Blocking Agents in Hereditary Recurrent Fevers: Data From the JIRcohort and a Literature Review.Frontiers in immunology · 2021Review
- Familial Mediterranean fever, from pathogenesis to treatment: a contemporary reviewTurkish journal of medical sciences · 2020Review
- The evaluation of anxiety, depression and quality of life scores of children and adolescents with familial Mediterranean fever.Rheumatology international · 2020Observational
- Anti-interleukin-1 treatment among patients with familial Mediterranean fever resistant to colchicine treatment. Retrospective analysis.Sao Paulo medical journal = Revista paulista de medicina · 2019Article
- Effect of interleukin-1 antagonists on the quality of life in familial Mediterranean fever patients.Clinical rheumatology · 2019Article
- On demand use of anakinra for attacks of familial Mediterranean fever (FMF).Clinical rheumatology · 2019Article
- [Evidence-based treatment recommendations for familial Mediterranean fever : A joint statement by the Society for Pediatric and Adolescent Rheumatology and the German Society for Rheumatology].Zeitschrift fur Rheumatologie · 2019Review
Corrections and comments
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Authors and funding
7 authors.
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Abstract
The aim of the present study was to investigate the health-related quality of life (HRQOL) and mood conditions in familial Mediterranean fever (FMF) patients. Ninety FMF patients (F/M 60/30, median age 29) and 67 control subjects (F/M 46/21, median age 30) were included in this study. HRQOL was assessed with short form-36 (SF-36) and mood conditions were assessed with hospital anxiety depression scale (HADS). FMF patients had significantly lower mean scores on SF-36 physical components compared to the control group. However, mental components were comparable between groups. FMF patients were significantly more likely to have depression and anxiety compared to the control group [30 (33%) vs. 8 (12%), respectively, χ (2) = 9.58, OR (95% CI) = 3.7 (1.5-8.7), p < 0.01 for depression and 48 (53%) and 11 (16%), respectively, χ (2) = 22.31, OR (95% CI) = 5.8 (2.7-12.5), p < 0.001 for anxiety]. When frequency of anxious subjects was adjusted for the presence of concomitant depressive status as a confounding factor, the difference between the groups remained statistically significant [χ (2) = 11.86, OR (95% CI) = 5.4 (2.1-13.7), p < 0.01]. However, the difference of depression status between groups was not statistically significant when adjusted for the presence of concomitant anxiety status [χ (2) = 0.08, OR (95% CI) = 1.3 (0.5-3.8), p = 0.78] and FMF was found to be independently associated with only anxiety [OR (95% CI) = 7.1 (2.3-20.3)]. In addition, pure anxious FMF subgroup had significantly lower scores of mental health and mental component summary when compared to normal mood subgroup. In conclusion, FMF might adversely affect HRQOL. Depression and anxiety are more frequent in FMF patients than healthy subjects.
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