ReviewWorld journal of surgery2010
Peritoneal damage: the inflammatory response and clinical implications of the neuro-immuno-humoral axis.
Review in World journal of surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Local Infiltration of Liposomal Bupivacaine on Opioid Consumption at Time of Cesarean Delivery: A Randomized Controlled Trial
Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy: A Randomized Controlled Trial
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis.World journal of surgery · 2015Pooled it
- Inflammatory response after open and laparoscopic Nissen fundoplication in children: a randomized study.Pediatric surgery international · 2014Trial
- The beneficial effects of preperitoneal catheter analgesia following colon and rectal resections: a prospective, randomized, double-blind, placebo-controlled study.Techniques in coloproctology · 2011Trial
- Analgesic efficacy of intraperitoneal local anaesthetic instillation (IPLA) in laparoscopic bariatric surgery: a systematic review and meta-analysis.Journal of anesthesia, analgesia and critical care · 2026Review
- Oral Administration Evaluation of the Hydro-Ethanolic Extract of Ginger (Rhizome ofEvidence-based complementary and alternative medicine : eCAM · 2023Article
- Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome.Experimental & molecular medicine · 2022Article
- Article
- Association of Abdominal Incision Length With Gastrointestinal Function Recovery Post-operatively: A Multicenter Registry System-Based Retrospective Cohort Study.Frontiers in surgery · 2021Article
- Laparoscopic procedures impact on mast cell mediators, extracellular matrix and adhesion scoring system in rats.Annals of medicine and surgery (2012) · 2020Article
- The effect of laparoscopy on mast cell degranulation and mesothelium thickness in rats.BMC surgery · 2020Article
- The role of the intra-abdominal view in complicated intra-abdominal infections.World journal of emergency surgery : WJES · 2019Article
- Inherited genetic predispositions in F13A1 and F13B genes predict abdominal adhesion formation: identification of gender prognostic indicators.Scientific reports · 2018Article
- Changes in the coelomic microclimate during carbon dioxide laparoscopy: morphological and functional implications.Pleura and peritoneum · 2017Article
- Surgical Site Infiltration for Abdominal Surgery: A Novel Neuroanatomical-based Approach.Plastic and reconstructive surgery. Global open · 2016Article
- Fast Track Surgery-Minimizing Side Effects of Surgery.The Indian journal of surgery · 2015Article
- A Novel Approach to Major Surgery: Tracking Its Pathophysiologic Footprints.World journal of surgery · 2015Article
- Preperitoneal catheter analgesia is an effective method for pain management after colorectal surgery: the results of 100 consecutive patients.Local and regional anesthesia · 2014Article
- Intraperitoneal wound in abdominal surgery.World journal of critical care medicine · 2013Article
- The Length of Surgical Skin Incision in Postoperative Inflammatory Reaction.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
- RoboticIn vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe peritoneum is a bilayer serous membrane that lines the abdominal cavity. We present a review of peritoneal structure and physiology, with a focus on the peritoneal inflammatory response to surgical injury and its clinical implications.
methodsWe conducted a nonsystematic clinical review. A search of the Ovid MEDLINE database from 1950 through January 2009 was performed using the following search terms: peritoneum, adhesions, cytokine, inflammation, and surgery.
resultsThe peritoneum is a metabolically active organ, responding to insult through a complex array of immunologic and inflammatory cascades. This response increases with the duration and extent of injury and is central to the concept of surgical stress, manifesting via a combination of systemic effects, and local neural pathways via the neuro-immuno-humoral axis. There may be a decreased systemic inflammatory response after minimally invasive surgery; however, it is unclear whether this is due to a reduced local peritoneal reaction.
conclusionsInterventions that dampen the peritoneal response and/or block the neuro-immuno-humoral pathway should be further investigated as possible avenues of enhancing recovery after surgery, and reducing postoperative complications.
Indexed as
Identifiers
20049432What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.