Evidence map›Paper›PMID 20049132›Full record

SynthesisEnvironmental health perspectives2009

Air pollution, aeroallergens, and emergency room visits for acute respiratory diseases and gastroenteric disorders among young children in six Italian cities.

Flavia Orazzo, Luigi Nespoli, Kazuhiko Ito, Davide Tassinari, Daniela Giardina, Maurizio Funis, Alessandra Cecchi, Chiara Trapani, Gisella Forgeschi, Massimo Vignini and 3 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Environmental health perspectives, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. PMMilitary Medical Research · 2017
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  19. Health of Children Living Near Coal Ash.Global pediatric health · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Flavia OrazzoPediatric Emergency Room, Santobono's Hospital, Naples, Italy.
Luigi Nespoli
Kazuhiko Ito
Davide Tassinari
Daniela Giardina
Maurizio Funis
Alessandra Cecchi
Chiara Trapani
Gisella Forgeschi
Massimo Vignini
Luana Nosetti
Sabrina Pigna
Antonella Zanobetti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPast studies reported evidence of associations between air pollution and respiratory symptoms and morbidity for children. Few studies examined associations between air pollution and emergency room (ER) visits for wheezing, and even fewer for gastroenteric illness. We conducted a multicity analysis of the relationship between air pollution and ER visits for wheezing and gastroenteric disorder in children 0-2 years of age.

methodsWe obtained ER visit records for wheezing and gastroenteric disorder from six Italian cities. A city-specific case-crossover analysis was applied to estimate effects of particulate matter (PM), nitrogen dioxide, sulfur dioxide, ozone, and carbon monoxide, adjusting for immediate and delayed effects of temperature. Lagged effects of air pollutants up to 6 prior days were examined. The city-specific results were combined using a random-effect meta-analysis.

resultsCO and SO(2) were most strongly associated with wheezing, with a 2.7% increase [95% confidence interval (CI), 0.5-4.9] for a 1.04-microg/m(3) increase in 7-day average CO and a 3.4% (95% CI, 1.5-5.3) increase for an 8.0-microg/m(3) increase in SO(2). Positive associations were also found for PM with aerodynamic diameter < or = 10 microg and NO(2). We found a significant association between the 3-day moving average CO and gastroenteric disorders [3.8% increase (95% CI, 1.0-6.8)]. When data were stratified by season, the associations were stronger in summer for wheezing and in winter for gastroenteric disorders.

conclusionAir pollution is associated with triggering of wheezing and gastroenteric disorders in children 0-2 years of age; more work is needed to understand the mechanisms to help prevent wheezing in children.

Indexed as

Acute DiseaseAir PollutantsAir PollutionAllergensCarbon MonoxideChild, PreschoolEmergency Service, HospitalGastrointestinal DiseasesHumansInfantInfant, NewbornItalyParticulate MatterRespiratory SoundsRespiratory Tract DiseasesSulfur DioxideAir PollutantsAllergensCarbon MonoxideParticulate MatterSulfur Dioxideair pollutionasthma in childrenchildren’s healthepidemiology of asthma

Identifiers

PMID20049132
PMCPMC2801171

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.