ArticleJournal of clinical hypertension (Greenwich, Conn.)2010
Secondary hypertension in overweight and stage 1 hypertensive children: a Midwest Pediatric Nephrology Consortium report.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of Secondary Hypertension in Otherwise Healthy Youths with a New Diagnosis of Hypertension: A Meta-Analysis.The Journal of pediatrics · 2022Pooled it
- Updated Guideline May Improve the Recognition and Diagnosis of Hypertension in Children and Adolescents; Review of the 2017 AAP Blood Pressure Clinical Practice Guideline.Current hypertension reports · 2017Pooled it
- Article
- Investigations for diagnosis of secondary hypertension in children: yield and costs.Pediatric nephrology (Berlin, Germany) · 2025Article
- Youth Blood Pressure and Target Organ Injury Markers: The SHIP AHOY Study.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Clinical guidelines for the diagnosis, evaluation, and management of hypertension for Korean children and adolescents: the Korean Working Group of Pediatric Hypertension.Kidney research and clinical practice · 2025Article
- Yield of diagnostic testing in evaluating etiology and end organ effects of pediatric hypertension.Pediatric nephrology (Berlin, Germany) · 2024Article
- Optimization of Personalized Amlodipine Dosing Strategies for Children Based on Pharmacokinetic Data from Chinese Male Adults and PBPK Modeling.Children (Basel, Switzerland) · 2021Article
- Characteristics of pediatric inpatients with primary and secondary hypertension.Pediatric investigation · 2021Article
- A reappraisal of the prevalence of pediatric hypertension through a nationwide database in Taiwan.Scientific reports · 2021Article
- Evaluation and Management of Stage 2 Hypertension in Pediatric Patients.Current hypertension reports · 2018Review
- Diagnosis and management of white-coat hypertension in children and adolescents: A Midwest Pediatric Nephrology Consortium study.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Clinical characteristics of hypertensive encephalopathy in pediatric patients.Korean journal of pediatrics · 2017Article
- Pharmacologic Management of Pediatric Hypertension.Paediatric drugs · 2016Review
- U.S. Preventive Services Task Force recommendation and pediatric hypertension screening: dereliction of duty or call to arms?Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
- Autonomic nervous system dysregulation in pediatric hypertension.Current hypertension reports · 2014Review
- Evaluation of hypertension in children.Current hypertension reports · 2013Review
- The changing face of pediatric hypertension in the era of the childhood obesity epidemic.Pediatric nephrology (Berlin, Germany) · 2013Review
- Treatment of obesity-related hypertension in children and adolescents.Current hypertension reports · 2013Review
- Prediction of primary vs secondary hypertension in children.Journal of clinical hypertension (Greenwich, Conn.) · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents, stage 1 hypertension is often primary in origin and associated with overweight. In contrast, stage 2 hypertension is more often secondary in origin and, hence, requires more extensive evaluation according to task force recommendations. The objective of this retrospective study was to evaluate whether the presence of stage 1 hypertension in overweight pediatric patients precludes workup for secondary hypertension (SH). This study included children (5-18 years) with hypertension (defined and staged per task force recommendations) referred to 4 pediatric nephrology centers in the Midwest region. Of the 246 referred patients, 166 patients with primary hypertension (PH) and SH were included for body mass index and hypertension stage analysis. The study revealed no significant differences in the mean age at diagnosis (PH, 13.1+/-3.1 years; SH, 12.4+/-3.8 years), distribution of overweight (PH, 89.4% BMI >85th percentile; SH, 80% BMI >85th percentile), and stage 1 (PH, 45%; SH, 40%) or 2 hypertensive (PH,55%; SH, 60%) children between PH vs SH. Overweight and presence of stage 1 hypertension should not preclude evaluation for SH.
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