Evidence map›Paper›PMID 20046993›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2009

Metallic Nanostructures as Localized Plasmon Resonance Enhanced Scattering Probes for Multiplex Dark Field Targeted Imaging of Cancer Cells.

Rui Hu, Ken-Tye Yong, Indrajit Roy, Hong Ding, Sailing He, Paras N Prasad

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Biology · 2025
    Article
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  4. Article
  5. Review
  6. Article
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  9. Review
  10. Probing the biological obstacles of nanomedicine with gold nanoparticles.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019
    Review
  11. Article
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  16. Review
  17. Article
  18. Biotechnology reports (Amsterdam, Netherlands) · 2014
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rui HuInstitute for Lasers, Photonics and Biophotonics, University at Buffalo, The State University of New York, Buffalo, New York 14260-4200, and Centre for Optical and Electromagnetic Research, Zhejiang University, Hangzhou 310058, China.
Ken-Tye Yong
Indrajit Roy
Hong Ding
Sailing He
Paras N Prasad

Funding

Multifunctional Nanoparticles in Diagnosis and Therapy of Pancreatic CancerR01CA119397 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PRASAD, PARAS N. · 2005 to 2009
$3.6M
NCI NIH HHS R01 CA119397
6 · The paper itself

Abstract

In this paper, we report the use of bioconjugated gold nanorods and silver nanoparticles as targeted localized surface plasmon resonance enhanced scattering probes for dark field multiplex and transmission electron microscopy (TEM) imaging of pancreatic cancer cells. We take advantage of the spectrally widely separated localized plasmon resonance of the gold nanorods and silver nanoparticles which produce wavelength selective plasmon resonance scattering to allow multiplex imaging with high contrast. By functionalizing the surfaces, aqueous dispersions of bioconjugated gold nanorods and silver nanoparticles are prepared. We demonstrate receptor-mediated delivery of bioconjugated gold nanorods and silver nanoparticles simultaneously into pancreatic cancer cells, using multiplexed dark field microscopy technique. We also show that the bioconjugated metallic nanostructures can be used for high contrast TEM imaging as well.

Identifiers

PMID20046993
PMCPMC2717617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.