ArticlePET clinics2009
Positron Emission Tomography Imaging of Hypoxia.
Article in PET clinics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- LnDOTA Releasing Probes for Luminescence and Magnetic Resonance Imaging.Inorganic chemistry · 2025Article
- A NIRS-Based Technique for Monitoring Brain Tissue Oxygenation in Stroke Patients.Sensors (Basel, Switzerland) · 2024Article
- Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions.Biosensors · 2022Review
- Detecting hypoxiaRSC advances · 2021Article
- An overview of the developments and potential applications ofAnnals of nuclear medicine · 2021Review
- Toward noninvasive quantification of adipose tissue oxygenation with MRI.International journal of obesity (2005) · 2020Article
- Article
- In vivo retinal and choroidal hypoxia imaging using a novel activatable hypoxia-selective near-infrared fluorescent probe.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Photoacoustic monitoring of tumor and normal tissue response to radiation.Scientific reports · 2016Article
- Evaluation of hypoxia with copper-labeled diacetyl-bis(N-methylthiosemicarbazone).Seminars in nuclear medicine · 2015Review
- Direct myocardial ischemia imaging: a new cardiovascular nuclear imaging paradigm.Clinical cardiology · 2015Review
- A prospective clinical study of ¹⁸F-FAZA PET-CT hypoxia imaging in head and neck squamous cell carcinoma before and during radiation therapy.European journal of nuclear medicine and molecular imaging · 2014Article
- PET radiopharmaceuticals for imaging of tumor hypoxia: a review of the evidence.American journal of nuclear medicine and molecular imaging · 2014Review
- Imaging radiation-induced normal tissue injury.Radiation research · 2012Review
- Tracer level electrophilic synthesis and pharmacokinetics of the hypoxia tracer [(18)F]EF5.Molecular imaging and biology · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Hypoxia imaging has applications in functional recovery in ischemic events such as stroke and myocardial ischemia, but especially in tumors in which hypoxia can be predictive of treatment response and overall prognosis. Recently there has been development of imaging agents utilizing positron emission tomography for non-invasive imaging of hypoxia. Many of these PET agents have come to the forefront of hypoxia imaging. Halogenated PET nitroimidazole imaging agents labeled with (18)F (t(1/2) = 110 m) and (124)I (t(1/2) = 110 m) have been under investigation for the last 25 years, with radiometal agents ((64)Cu-ATSM) being developed more recently. This review focuses on these positron emission tomography imaging agents for hypoxia.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.