ReviewNeuropharmacology2010
Primary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link?
Review in Neuropharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Glioma-neuron interactions: insights from neural plasticity.Frontiers in oncology · 2025Review
- Translational Models in Glioma Immunotherapy Research.Current oncology (Toronto, Ont.) · 2023Review
- BLM helicase overexpressed in human gliomas contributes to diverse responses of human glioma cells to chemotherapy.Cell death discovery · 2023Article
- Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery.Pharmaceutics · 2023Article
- Bio-Prospecting of Crude Leaf Extracts from Thirteen Plants of Brazilian Cerrado Biome on Human Glioma Cell Lines.Molecules (Basel, Switzerland) · 2023Article
- A rare, pediatric, fourth-ventricular, anaplastic astrocytoma.Radiology case reports · 2021Article
- A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation.Frontiers in chemistry · 2019Article
- Article
- Article
- miR-1297 regulates neural stem cell differentiation and viability through controlling Hes1 expression.Cell proliferation · 2017Article
- Neural stem cell transplantation for the treatment of primary torsion dystonia: A case report.Experimental and therapeutic medicine · 2016Article
- Medulloepithelioma with peculiar clinical presentation, stem cell phenotype and aberrant DNA-methylation profile.CNS oncology · 2015Article
- Stem cells and gliomas: past, present, and future.Journal of neuro-oncology · 2014Review
- Cell cycle regulation during neurogenesis in the embryonic and adult brain.Stem cell reviews and reports · 2013Review
- Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway.Neuro-oncology · 2013Article
- Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1alpha expression.Journal of neurochemistry · 2013Article
- Imaging glioma initiation in vivo through a polished and reinforced thin-skull cranial window.Journal of visualized experiments : JoVE · 2012Article
- Characteristic features of stem cells in glioblastomas: from cellular biology to genetics.Brain pathology (Zurich, Switzerland) · 2012Review
- Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.Cancer research · 2012Article
- Stem cells as therapeutic vehicles for the treatment of high-grade gliomas.Neuro-oncology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The discovery of brain tumor-derived cells (BTSC) with the properties of stem cells has led to the formulation of the hypothesis that neural stem cells could be the cell of origin of primary brain tumors (PBT). In this review we present the most common molecular changes in PBT, define the criteria of identification of BTSC and discuss the similarities between the characteristics of these cells and those of the endogenous population of neural stem cells (NPCs) residing in germinal areas of the adult brain. Finally, we propose possible mechanisms of cancer initiation and progression and suggest a model of tumor initiation that includes intrinsic changes of resident NSC and potential changes in the microenvironment defining the niche where the NSC reside.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.