ArticleBioTechniques2009
A device for the simple and rapid transcervical transfer of mouse embryos eliminates the need for surgery and potential post-operative complications.
Article in BioTechniques, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 58 citations in OpenAlex.
- Effects of multimodal analgesia on the success of mouse embryo transfer surgery.Journal of the American Association for Laboratory Animal Science : JAALAS · 2011Trial
- Elevated contractility drives implantation failure in mouse embryos from aged females.Nature cell biology · 2026Article
- Screening of nontoxic dyes for improved visualization and success rate in mouse embryo transfer.Laboratory animal research · 2025Article
- A mechanical origin for implantation defects in embryos from aged females.bioRxiv : the preprint server for biology · 2025Article
- Astaxanthin prevents postovulatory oocyte aging by targeting TNFR2 and inhibiting the TNF signaling pathway.BMC biology · 2025Article
- Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination.Journal of visualized experiments : JoVE · 2023Article
- IL11 activates the placental inflammasome to drive preeclampsia.Frontiers in immunology · 2023Article
- Placental deficiency of the (pro)renin receptor ((P)RR) reduces placental development and functional capacity.Frontiers in cell and developmental biology · 2023Article
- Review
- Probing morphological, genetic and metabolomic changes of in vitro embryo development in a microfluidic device.Biotechnology progress · 2021Article
- Male-derived copulatory plugs enhance implantation success in female Mus musculus.Biology of reproduction · 2021Article
- Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit.Nature communications · 2021Article
- Assisted Hatching Treatment of Piezo-Mediated Small Hole on Zona Pellucida in Morula Stage Embryos Improves Embryo Implantation and Litter Size in Mice.Frontiers in cell and developmental biology · 2021Article
- Hypermethylation and reduced expression of Gtl2, Rian and Mirg at the Dlk1-Dio3 imprinted locus as a marker for poor developmental potential of mouse embryonic stem cells.Stem cell research · 2020Article
- A Nonsurgical Embryo Transfer Technique for Fresh and Cultured Blastocysts in Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Media optimization to promote rat embryonic development to the blastocyst stage in vitro.Theriogenology · 2020Article
- Blastocyst hatching site is regularly distributed and does not influence foetal development in mice.Scientific reports · 2020Article
- A human-based assisted reproduction protocol for the menstruating spiny mouse, Acomys cahirinus.PloS one · 2020Article
- Simplified pipelines for genetic engineering of mammalian embryos by CRISPR-Cas9 electroporation†.Biology of reproduction · 2019Article
- Effect of Predator Stress on the Reproductive Performance of Female Mice After Nonsurgical Embryo Transfer.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
We describe a novel device that can be used for the transcervical transfer of embryos into pseudopregnant female mice. This nonsurgical embryo transfer (NSET) device is as efficient as standard surgical embryo transfer in the production of transgenic mice, and can also be used for the transfer of embryonic stem cell-containing chimeric blastocysts and cryopreserved embryos. In addition to the elimination of surgery, recipient females do not have to be anesthetized. The NSET device eliminates a painful surgical procedure as well as potential complications associated with anesthesia/post-operative care, reduces the technical expertise and equipment needed for surgical transfer, and represents substantial cost savings and regulatory reduction. NSET technology provides an easy and rapid alternative to surgical embryo transfer. Address correspondence to Brett Spear, Room 210, Combs Building, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY, 40536-0298, USA. email:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.