Evidence map›Paper›PMID 20041042›Full record

ReviewAlcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism2008

Translational studies of alcoholism: bridging the gap.

Natalie M Zahr, Edith V Sullivan

Abstract readReview
In one paragraph

Review in Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Shared genetic factors influence amygdala volumes and risk for alcoholism.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
    Article
  3. Alcohol: the lubricant to suicidality.Innovations in clinical neuroscience · 2013
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Magnetic resonance imaging of the living brain: evidence for brain degeneration among alcoholics and recovery with abstinence.Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2008
    Review
  9. Alcohol-induced structural and cellular brain alterations: molecular and histopathological mechanisms.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natalie M ZahrNatalie M. Zahr, Ph.D., is a postdoctoral fellow at SRI International, Menlo Park, California, and a research scientist with professor Edith V. Sullivan, Ph.D., who is a professor in the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California.
Edith V Sullivan

Funding

CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISMR01AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI, ZAHR, NATALIE M · 1996 to 2025
$8.3M
Cerebellar Structure and Function in AlcoholismR37AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2010 to 2019
$5.4M
Translational Studies of Brain Circuitry Disrupted by AlcoholismK05AA017168 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2008 to 2017
$2.2M
NIAAA NIH HHS AA010723NIAAA NIH HHS AA017168NIAAA NIH HHS K05 AA017168NIAAA NIH HHS R01 AA010723NIAAA NIH HHS R37 AA010723
6 · The paper itself

Abstract

Human studies are necessary to identify and classify the brain systems predisposing individuals to develop alcohol use disorders and those modified by alcohol, while animal models of alcoholism are essential for a mechanistic understanding of how chronic voluntary alcohol consumption becomes compulsive, how brain systems become damaged, and how damage resolves. Our current knowledge of the neuroscience of alcohol dependence has evolved from the interchange of information gathered from both human alcoholics and animal models of alcoholism. Together, studies in humans and animal models have provided support for the involvement of specific brain structures over the course of alcohol addiction, including the prefrontal cortex, basal ganglia, cerebellum, amygdala, hippocampus, and the hypothalamic-pituitary-adrenal axis.

Indexed as

Disease Models, AnimalAlcohol DrinkingAlcoholismAnimalsBrainEthanolHumansNerve NetTranslational Research, BiomedicalEthanolalcohol and other drug effects and consequencesAlcohol dependencealcoholismanimal modelsanimal studiesbrainchronic alcohol exposureenvironmental factorsgenetic factorshuman studiesneurobiologytranslational studies

Identifiers

PMID20041042
PMCPMC2798743

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.