ArticleThe Journal of biological chemistry2010
Preferential KAT1-KAT2 heteromerization determines inward K+ current properties in Arabidopsis guard cells.
Article in The Journal of biological chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 72 citations in OpenAlex.
- Expansion and Functional Divergence of Shaker KInternational journal of molecular sciences · 2026Article
- Structural changes in the conversion of an Arabidopsis outward-rectifying KPlant communications · 2024Article
- Research Progress on Plant Shaker KPlants (Basel, Switzerland) · 2024Review
- Article
- Determination of protoplast growth properties using quantitative single-cell tracking analysis.Plant methods · 2022Article
- Non-autonomous stomatal control by pavement cell turgor via the K+ channel subunit AtKC1.The Plant cell · 2022Article
- Multiple ALMT subunits combine to form functional anion channels: A case study for rice ALMT7.Frontiers in plant science · 2022Article
- Controlling the Gate: The Functions of the Cytoskeleton in Stomatal Movement.Frontiers in plant science · 2022Review
- Structural and Functional Insights into the Role of Guard Cell Ion Channels in Abiotic Stress-Induced Stomatal Closure.Plants (Basel, Switzerland) · 2021Review
- Adjustment of KInternational journal of molecular sciences · 2021Review
- CaInternational journal of molecular sciences · 2021Article
- The Complex Story of Plant Cyclic Nucleotide-Gated Channels.International journal of molecular sciences · 2021Review
- The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.PLoS biology · 2020Article
- The Shaker Type Potassium Channel, GORK, Regulates Abscisic Acid Signaling in Arabidopsis.The plant pathology journal · 2019Article
- Unique features of the grapevine VvK5.1 channel support novel functions for outward K+ channels in plants.Journal of experimental botany · 2019Article
- BCL2-ASSOCIATED ATHANOGENE4 Regulates the KAT1 Potassium Channel and Controls Stomatal Movement.Plant physiology · 2019Article
- Review
- The Complex Fine-Tuning of K⁺ Fluxes in Plants in Relation to Osmotic and Ionic Abiotic Stresses.International journal of molecular sciences · 2019Review
- Regulation of KFrontiers in plant science · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guard cells adjust their volume by changing their ion content due to intense fluxes that, for K(+), are believed to flow through inward or outward Shaker channels. Because Shaker channels can be homo- or heterotetramers and Arabidopsis guard cells express at least five genes encoding inward Shaker subunits, including the two major ones, KAT1 and KAT2, the molecular identity of inward Shaker channels operating therein is not yet completely elucidated. Here, we first addressed the properties of KAT1-KAT2 heteromers by expressing KAT1-KAT2 tandems in Xenopus oocytes. Then, computer analyses of the data suggested that coexpression of free KAT1 and KAT2 subunits resulted mainly in heteromeric channels made of two subunits of each type due to some preferential association of KAT1-KAT2 heterodimers at the first step of channel assembly. This was further supported by the analysis of KAT2 effect on KAT1 targeting in tobacco cells. Finally, patch-clamp recordings of native inward channels in wild-type and mutant genotypes strongly suggested that this preferential heteromerization occurs in planta and that Arabidopsis guard cell inward Shaker channels are mainly heteromers of KAT1 and KAT2 subunits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.