ArticleInternational journal of legal medicine2010
Pulmonary arteriovenous malformation causing sudden death due to spontaneous hemothorax.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Massive hemothorax induced by pulmonary arteriovenous malformation rupture: a case report and literature review.Journal of cardiothoracic surgery · 2024Review
- Sudden pediatric death unveiling pulmonary arteriovenous malformations.Autopsy & case reports · 2024Article
- Case report: Pulmonary arterial hypertension inFrontiers in cardiovascular medicine · 2022Article
- Comorbidity among HHT patients and their controls in a 20 years follow-up period.Orphanet journal of rare diseases · 2018Article
- Back to the Future - Part 1. The medico-legal autopsy from ancient civilization to the post-genomic era.International journal of legal medicine · 2017Review
- 20-year follow-up study of Danish HHT patients-survival and causes of death.Orphanet journal of rare diseases · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A sudden death due to hemothorax caused by spontaneous rupture of a congenital pulmonary arteriovenous malformation (AVM) is reported. A 44-year-old woman died unexpectedly with chest pain and dyspnea. The post-mortem examination revealed a massive right-sided hemothorax arising from a subpleural AVM of the upper lobe. There were multiple telangiectases in the tongue and the tonsils, as typically associated with Osler-Weber-Rendu disease (hereditary hemorrhagic telangiectasia, HHT). The post-mortem molecular genetic analysis proved the presence of a disease-causing mutation in the endoglin gene constituting a predisposition for pulmonary AVMs. According to the literature, almost half of the AVMs in the lung are seen in HHT patients. Based on the presented case and the relevant literature, the article addresses the forensic aspects of fatal hemothorax and the importance of detecting the source of bleeding.
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Registered trials
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