ArticleJournal of molecular evolution2010
The chicken Z chromosome is enriched for genes with preferential expression in ovarian somatic cells.
Article in Journal of molecular evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.Endocrinology · 2021Article
- Masculinization of the x chromosome in the pea aphid.PLoS genetics · 2013Article
- Retrogenes moved out of the z chromosome in the silkworm.Journal of molecular evolution · 2012Article
- Small but mighty: the evolutionary dynamics of W and Y sex chromosomes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
- Emergence of male-biased genes on the chicken Z-chromosome: sex-chromosome contrasts between male and female heterogametic systems.Genome research · 2011Article
- Sex-chromosome evolution: recent progress and the influence of male and female heterogamety.Nature reviews. Genetics · 2011Review
- The resolution of sexual antagonism by gene duplication.Genetics · 2011Article
- Gene duplication and the genome distribution of sex-biased genes.International journal of evolutionary biology · 2011Article
- Sex linkage, sex-specific selection, and the role of recombination in the evolution of sexually dimorphic gene expression.Evolution; international journal of organic evolution · 2010Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theory predicts that sexually antagonistic mutations will be over- or under-represented on the X and Z chromosomes, depending on their average dominance coefficients. However, as little is known about the dominance coefficients for new mutations, the effect of sexually antagonistic selection is difficult to predict. To elucidate the role of sexually antagonistic selection in the evolution of Z chromosome gene content in chicken, we analyzed publicly available microarray data from several somatic tissues as well as somatic and germ cells of the ovary. We found that the Z chromosome is enriched for genes showing preferential expression in ovarian somatic cells, but not for genes with preferential expression in primary oocytes or non-sex-specific somatic tissues. Our results suggest that sexual antagonism leads to a higher abundance of female-benefit alleles on the Z chromosome. No bias toward Z-linkage for oocyte-enriched genes can be explained by lower intensity of sexually antagonistic selection in ovarian germ cells compared to ovarian somatic cells. An alternative explanation would be that meiotic Z chromosome inactivation hinders accumulation of oocyte-expressed genes on the Z chromosome. Our results are consistent with findings in mammals and indicate that recessive rather than dominant sexually antagonistic mutations shape the gene content of the X and Z chromosomes.
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