Evidence map›Paper›PMID 20037711›Full record

ReviewClinics (Sao Paulo, Brazil)2009

The chronic gastrointestinal manifestations of Chagas disease.

Nilce Mitiko Matsuda, Steven M Miller, Paulo R Barbosa Evora

Open access · goldAbstract readReview
In one paragraph

Review in Clinics (Sao Paulo, Brazil), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Gastrointestinal Manifestations of Chagas Disease: A Systematic Review with Meta-Analysis.The American journal of tropical medicine and hygiene · 2024
    Pooled it
  2. Pooled it
  3. MINIMALLY INVASIVE LAPAROSCOPIC ESOPHAGECTOMY VS. TRANSHIATAL OPEN ESOPHAGECTOMY IN ACHALASIA: A RANDOMIZED STUDY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2018
    Trial
  4. Double negative T cells (CD4Frontiers in immunology · 2026
    Article
  5. Oral Route Infection byPathogens (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Forensic considerations in cases of fatal constipation.Forensic science, medicine, and pathology · 2025
    Review
  8. Apoptosis: A Key Process ThatJournal of parasitology research · 2025
    Review
  9. Article
  10. Article
  11. Chagas Disease: A Silent Threat for Dogs and Humans.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Review
  14. Pathogens (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Frontiers in cellular and infection microbiology · 2023
    Article
  18. Frontiers in cell and developmental biology · 2023
    Review
  19. Article
  20. Observational

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Nilce Mitiko MatsudaDepartamento de Anatomia e Cirurgia, Universidade de São Paulo - Ribeirão Preto/SP, Brazil. nmmatsuda@uol.com.br
Steven M Miller
Paulo R Barbosa Evora
Universidade de Ribeirão Preto · BRMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease is an infectious disease caused by the protozoan Trypanosoma cruzi. The disease mainly affects the nervous system, digestive system and heart. The objective of this review is to revise the literature and summarize the main chronic gastrointestinal manifestations of Chagas disease. The chronic gastrointestinal manifestations of Chagas disease are mainly a result of enteric nervous system impairment caused by T. cruzi infection. The anatomical locations most commonly described to be affected by Chagas disease are salivary glands, esophagus, lower esophageal sphincter, stomach, small intestine, colon, gallbladder and biliary tree. Chagas disease has also been studied in association with Helicobacter pylori infection, interstitial cells of Cajal and the incidence of gastrointestinal cancer.

Indexed as

Chagas DiseaseChronic DiseaseGastrointestinal DiseasesHumansChagas disease, Trypanosoma cruziEnteric nervous systemGastrointestinal tractMotility disorders

Identifiers

PMID20037711
PMCPMC2797592
OpenAlexW1984194904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.