Evidence map›Paper›PMID 20034426›Full record

ReviewComparative medicine2009

Acute phase response in animals: a review.

Carolyn Cray, Julia Zaias, Norman H Altman

Open access · greenAbstract readReview
In one paragraph

Review in Comparative medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 318 papers.

0numbers the graph read from it
0cells of the map it votes in
318citing papers in PubMed
33.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

318 citing papers in PubMed, 681 citations in OpenAlex.

  1. Article
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  6. Article
  7. Review
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  9. Article
  10. Clinicopathological abnormalities and outcome of acuteCurrent research in parasitology & vector-borne diseases · 2026
    Article
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  18. Concentrations of Progesterone (PVeterinary sciences · 2025
    Article
  19. Article
  20. Article

258 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carolyn CrayDivision of Comparative Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA. c.cray@miami.edu
Julia Zaias
Norman H Altman
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acute phase response is a complex systemic early-defense system activated by trauma, infection, stress, neoplasia, and inflammation. Although nonspecific, it serves as a core of the innate immune response involving physical and molecular barriers and responses that serve to prevent infection, clear potential pathogens, initiate inflammatory processes, and contribute to resolution and the healing process. Acute phase proteins, an integral part of the acute phase response, have been a focus of many applications in human diagnostic medicine and recently have been identified in common animal species. Potential applications to diagnosis, prognosis, assessment of animal health, and laboratory animal welfare are readily apparent.

Indexed as

Acute-Phase ReactionAcute-Phase ProteinsAnimalsC-Reactive ProteinInflammationPrognosisSerum Amyloid A ProteinAcute-Phase ProteinsC-Reactive ProteinSerum Amyloid A Protein

Identifiers

PMID20034426
PMCPMC2798837
OpenAlexW199757098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.