ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2010
Transcriptional regulatory regions of gap43 needed in developing and regenerating retinal ganglion cells.
Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Ginsenoside-Rb1 for Ischemic Stroke: A Systematic Review and Meta-analysis of Preclinical Evidence and Possible Mechanisms.Frontiers in pharmacology · 2020Pooled it
- Bridging the anatomical gap: evolutionary conservation of genetic mechanisms in corpus callosum disorders across human, mouse, and zebrafish.Frontiers in molecular neuroscience · 2026Review
- Serotonin neuromodulation directs optic nerve regeneration.Development (Cambridge, England) · 2025Article
- Deletion of Slc1a4 Suppresses Single Mauthner Cell Axon Regeneration In Vivo through Growth-Associated Protein 43.International journal of molecular sciences · 2024Article
- Acute myocardial infarction induces remodeling of the murine superior cervical ganglia and the carotid body.Frontiers in cardiovascular medicine · 2022Article
- Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors.Scientific reports · 2019Article
- Optic nerve regeneration: A long view.Restorative neurology and neuroscience · 2019Review
- Axonal regeneration in zebrafish spinal cord.Regeneration (Oxford, England) · 2018Review
- AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury.Neural plasticity · 2017Article
- Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation.Journal of the American Society of Nephrology : JASN · 2016Article
- Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration.BMC genomics · 2015Article
- Characterization of optic nerve regeneration using transgenic zebrafish.Frontiers in cellular neuroscience · 2015Article
- Article
- Different mechanisms regulate expression of zebrafish myelin protein zero (P0) in myelinating oligodendrocytes and its induction following axonal injury.The Journal of biological chemistry · 2014Article
- Ectopic expression of transcription factor AP-2δ in developing retina: effect on PSA-NCAM and axon routing.Journal of neurochemistry · 2014Article
- Far upstream element binding protein 1: a commander of transcription, translation and beyond.Oncogene · 2013Review
- Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Genetic dissection of axon regeneration.Current opinion in neurobiology · 2011Review
- Extrinsic and intrinsic determinants of nerve regeneration.Journal of tissue engineering · 2011Article
- Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves.The Journal of biological chemistry · 2010Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Mammals and fish differ in their ability to express axon growth-associated genes in response to CNS injury, which contributes to the differences in their ability for CNS regeneration. Previously we demonstrated that for the axon growth-associated gene, gap43, regions of the rat promoter that are sufficient to promote reporter gene expression in the developing zebrafish nervous system are not sufficient to promote expression in regenerating retinal ganglion cells in zebrafish. Recently, we identified a 3.6-kb gap43 promoter fragment from the pufferfish, Takifugu rubripes (fugu), that can promote reporter gene expression during both development and regeneration. Using promoter deletion analysis, we have found regions of the 3.6-kb fugu gap43 promoter that are necessary for expression in regenerating, but not developing, retinal ganglion cells. Within the 3.6-kb promoter, we have identified elements that are highly conserved among fish, as well as elements conserved among fish, mammals, and birds.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.