Evidence map›Paper›PMID 20033884›Full record

ArticleInternational journal of methods in psychiatric research2009

The structure of mental disorders re-examined: is it developmentally stable and robust against additions?

Hans-Ulrich Wittchen, Katja Beesdo-Baum, Andrew T Gloster, Michael Höfler, Jens Klotsche, Roselind Lieb, André Beauducel, Markus Bühner, Ronald C Kessler

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Common Cause Versus Dynamic Mutualism: An Empirical Comparison of Two Theories of Psychopathology in Two Large Longitudinal Cohorts.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  3. The Hierarchical Taxonomy of Psychopathology (HiTOP) Is Not an Improvement Over the DSM.Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
  4. Folk Classification and Factor Rotations: Whales, Sharks, and the Problems With the Hierarchical Taxonomy of Psychopathology (HiTOP).Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
  5. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  6. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
  7. Article
  8. Article
  9. "Throwing out the baby with the bathwater"? Conceptual and methodological limitations of the HiTOP approach.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018
    Article
  10. Article
  11. Article
  12. Toward a Functional View of the P Factor in Psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2017
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative.Journal of child psychology and psychiatry, and allied disciplines · 2015
    Article
  18. Review
  19. Review
  20. Transdiagnostic factors of psychopathology and substance use disorders: a review.Social psychiatry and psychiatric epidemiology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hans-Ulrich WittchenInstitute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany. wittchen@psychologie.tu-dresden.de
Katja Beesdo-Baum
Andrew T Gloster
Michael Höfler
Jens Klotsche
Roselind Lieb
André Beauducel
Markus Bühner
Ronald C Kessler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research suggests that patterns of comorbidity of a limited number of anxiety, depressive, substance use and antisocial personality (ASP) disorders among adults are best reflected by a hierarchical three-factor structure with two correlated factors ('anxious-misery' and 'fear') that are summarized in a second-order 'internalizing' factor and one 'externalizing' factor. It has not been examined whether this structure is developmentally stable and robust against additions of more diagnoses. Using data from a prospective-longitudinal community study of adolescents and young adults we re-evaluate the three-factor model originally proposed by Krueger (Archives of General Psychiatry, 1999; 56, 921-926). Using confirmatory factor analysis with identical conventions as in Krueger's original work we found that the three factor model did not fit robustly across age or a wider range of diagnoses. Using explanatory factor analysis we examined alternative structures. We found various clinically meaningful patterns with good fit that go substantially beyond the original three-factor structure. However, again, there is little consistency in findings when different age groups or different diagnoses are considered. Our findings suggest that psychopathology cannot be reduced to any simple structure.

Indexed as

Models, PsychologicalPsychiatric Status Rating ScalesAdolescentAdultAge FactorsChildChild, PreschoolComorbidityDiagnostic and Statistical Manual of Mental DisordersFactor Analysis, StatisticalFemaleHumansInfantLongitudinal StudiesMaleMental Disorders

Identifiers

PMID20033884
PMCPMC6878396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.