Evidence map›Paper›PMID 20033844›Full record

ArticleDigestive diseases and sciences2010

Association of intussusception and celiac disease in adults.

Tamas A Gonda, Sharif-Uz-Zaman Khan, Jian Cheng, Suzanne K Lewis, Moshe Rubin, Peter H R Green

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Unfolding the diagnosis: A rare presentation of celiac disease in an adult.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
  10. A case of adult intussusception.BMJ case reports · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. [A rare cause of recurrent small bowel intussusception. Case report and review of the literature].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2012
    Review
  18. Article
  19. Article
  20. Adult intussusception in the last 25 years of modern imaging: is surgery still indicated?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tamas A GondaDivision of Digestive and Liver Diseases, Department of Medicine, Celiac Disease Center, Columbia University Medical Center, New York, NY, USA. tg2214@columbia.edu
Sharif-Uz-Zaman Khan
Jian Cheng
Suzanne K Lewis
Moshe Rubin
Peter H R Green
Columbia University Irving Medical Center · USNew York Hospital Queens · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntussusception (IS) is rare in adults. However, the more frequent use of cross-sectional imaging has resulted in an increase in its detection. Because of the reported association with celiac disease, we determined the prevalence of IS among a cohort with celiac disease.

methodsAn anonymized prospectively maintained celiac disease database and radiological database were reviewed.

resultsOf a total of 880 patients, 14 (age 47 ± 17.5 years; 50% female) had IS that was detected by CT in 10, capsule endoscopy in three, and barium studies in two. The reason for evaluation was abdominal pain in 78% (11/14), whereas in the remainder (3/14) were incidental. IS was the initial manifestation of celiac disease in 57% (8/14). Two patients were found to have lead-point intussusceptions and both had small-bowel adenocarcinoma, and 10/14 had severe villous atrophy (subtotal or total). Among those with established celiac disease, IS was detected early, within 3 years of diagnosis. Follow-up was available for 11 patients, 9 of who adhered strictly to a gluten-free diet, and six had no recurrence. Among all the patients diagnosed with IS on radiologic studies at our institution, 45 were considered to have idiopathic IS. Only two of these patients had evaluation for celiac disease.

conclusionIS occurs in celiac disease. It may be the initial presentation and is associated with abdominal pain. Adenocarcinoma needs to be excluded. The majority of patients do not have recurrent symptoms after adherence to a gluten-free diet. Celiac disease should be considered more frequently when IS is encountered.

Indexed as

Abdominal PainAdenocarcinomaAdultAtrophyBiopsyCapsule EndoscopyCeliac DiseaseChi-Square DistributionDatabases, FactualFemaleFollow-Up StudiesHumansIncidental FindingsIntestinal NeoplasmsIntussusceptionMale

Identifiers

PMID20033844
OpenAlexW2157387617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.