ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2010
Functional and molecular evolution of olfactory neurons and receptors for aliphatic esters across the Drosophila genus.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed.
- Receptor sequence divergence, gain, loss, duplication, and neofunctionalization drive olfactory adaptation inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Experimental assessment of 3D-printed traps and chemical attractants for the collection of wildFly · 2025Article
- Divergent Evolutionary Pressures Shape Olfactory Sensitivity of the Maxillary Palps in Tephritidae Fruit Flies.Ecology and evolution · 2025Article
- Genomic plasticity drives olfactory adaptation in a pest fly.bioRxiv : the preprint server for biology · 2025Article
- Olfactory variation among closely related cactophilic Drosophila species.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
- Microbiome-emitted scents activate olfactory neuron-independent airway-gut-brain axis to promote host growth in Drosophila.Nature communications · 2025Article
- Evolution of Sensory Receptors.Annual review of cell and developmental biology · 2024Review
- Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking.Nature communications · 2024Article
- Temperature-dependent modulation of odor-dependent behavior in three drosophilid fly species of differing thermal preference.Communications biology · 2023Article
- Odor-regulated oviposition behavior in an ecological specialist.Nature communications · 2023Article
- Functional olfactory evolution iniScience · 2022Article
- Natural variation at theOpen biology · 2021Article
- Sequence-Based Prediction of Olfactory Receptor Responses.Chemical senses · 2019Article
- Molecular and Functional Evolution at the Odorant Receptor Or22 Locus in Drosophila melanogaster.Molecular biology and evolution · 2019Article
- Article
- Evolutionary ecology of chemosensation and its role in sensory drive.Current zoology · 2018Article
- Patterns of transcriptional parallelism and variation in the developing olfactory system of Drosophila species.Scientific reports · 2017Article
- Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center.BMC biology · 2016Article
- Population differences in olfaction accompany host shift in Drosophila mojavensis.Proceedings. Biological sciences · 2016Article
- The Evolution of Olfactory Gene Families in Drosophila and the Genomic Basis of chemical-Ecological Adaptation in Drosophila suzukii.Genome biology and evolution · 2016Article
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4 authors.
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Abstract
Insect olfactory receptor (Or) genes are large, rapidly evolving gene families of considerable interest for evolutionary studies. They determine the responses of sensory neurons which mediate critical behaviours and ecological adaptations. We investigated the evolution across the genus Drosophila of a subfamily of Or genes largely responsible for the perception of ecologically relevant aliphatic esters; products of yeast fermentation and fruits. Odour responses were recorded from eight classes of olfactory receptor neurons known to express this Or subfamily in D. melanogaster and from homologous sensilla in seven other species. Despite the fact that these species have diverged over an estimated 40 million years, we find that odour specificity is largely maintained in seven of the eight species. In contrast, we observe extensive changes in most neurons of the outgroup species D. virilis, and in two neurons across the entire genus. Some neurons show small shifts in specificity, whilst some dramatic changes correlate with gene duplication or loss. An olfactory receptor neuron response similarity tree did not match an Or sequence similarity tree, but by aligning Or proteins of likely functional equivalence we identify residues that may be relevant for odour specificity. This will inform future structure-function studies of Drosophila Ors.
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