Evidence map›Paper›PMID 20031875›Full record

ArticleCirculation. Cardiovascular quality and outcomes2009

Trends in 10-year predicted risk of cardiovascular disease in the United States, 1976 to 2004.

Francisco Lopez-Jimenez, John A Batsis, Véronique L Roger, Lee Brekke, Henry H Ting, Virend K Somers

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francisco Lopez-JimenezDivisions of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. lopez@mayo.edu
John A Batsis
Véronique L Roger
Lee Brekke
Henry H Ting
Virend K Somers
Dartmouth–Hitchcock Medical Center · US

Funding

ZESTRIL VS. VERAPAMIL IN THE TREATMENT OF HYPERTENSIONM01RR000585 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 1985 to 2006
$30.4M
Heart Failure in the CommunityR01HL072435 · NHLBI · MAYO CLINIC ROCHESTER · PI ROGER, VERONIQUE LEE · 2003 to 2011
$6.0M
Disease Mechanisms in Sleep ApneaR01HL065176 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 1999 to 2021
$5.8M
CORONARY DISEASE MORBIDITY AND MORTALITY IN A POPULATIONR01HL059205 · NHLBI · MAYO CLINIC ROCHESTER · PI ROGER, VERONIQUE LEE · 1998 to 2012
$4.6M
Fat Gain and Cardiovascular Disease MechanismsR01HL073211 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2003 to 2007
$1.8M
Neural Circulatory Control in the Long QT SyndromeR01HL070302 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2002 to 2006
$1.6M
Molecular Mechanisms Mediating Resistance to Leptin Signaling During Fat GainR21DK081014 · NIDDK · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2008 to 2009
$416k
Sleep Deprivation and Energy BalanceR21HL096071 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2009 to 2010
$407k
NCRR NIH HHS M01 RR000585NCRR NIH HHS M01-RR00585NHLBI NIH HHS HL 096071NHLBI NIH HHS HL 59205NHLBI NIH HHS HL-65176NHLBI NIH HHS HL 72435NHLBI NIH HHS R01 HL059205NHLBI NIH HHS R01 HL065176NHLBI NIH HHS R01 HL070302NHLBI NIH HHS R01 HL072435NHLBI NIH HHS R01 HL073211NIDDK NIH HHS DK 081014NIDDK NIH HHS R21 DK081014
6 · The paper itself

Abstract

backgroundThere have been significant bidirectional changes in the prevalence of cardiovascular (CV) risk factors over time in the United States, making the net trend in risk for incident CV disease unknown. We assessed these trends by applying the Framingham Heart Study prediction model to national data. METHODS AND

resultsThe National Health and Nutrition Examination Survey (NHANES) II (1976-1980), NHANES III (1988-1994), and NHANES 1999-2004 are cross-sectional representative samples of the noninstitutionalized population of the United States. We excluded people with a history of CV disease, pregnant women, participants with missing CV risk factors data, and individuals outside the Framingham age range of 30 to 74 years. The Framingham risk function was used to estimate the 10-year risk for incident symptomatic CV disease. We calculated the slope of change or rate of change per year between NHANES II and III, and between NHANES III and 1999-2004. The difference between slopes was calculated and compared to zero. The average age-adjusted 10-year CV risk between NHANES II and III decreased from 10.0% to 7.9% between NHANES II and III, with a statistically significant slope (P<0.001). However, the average age-adjusted CV risk decreased at a lesser magnitude between NHANES III and NHANES 1999-2004 from 7.9% to 7.4% (P<0.001). These slopes were significantly different (P<0.0001). In women and middle-aged participants, CV risk did not change between NHANES III and NHANES 1999-2004 (P=0.40).

conclusionsThe estimated net risk for CV disease in the US population decreased from 1976-1980 to 1988-1994 but has changed minimally from 1988-1994 to 1999-2004, particularly in women and middle-aged people.

Indexed as

Age DistributionCardiovascular DiseasesDiabetes MellitusFemaleHumansHyperglycemiaHyperlipidemiasHypertensionIncidenceMaleMiddle AgedNutrition SurveysObesityPredictive Value of TestsPrevalenceRisk Factors

Identifiers

PMID20031875
PMCPMC2779550
OpenAlexW2124005678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.