ArticleGut pathogens2009
Helicobacter pylori--a seasoned pathogen by any other name.
Article in Gut pathogens, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Climate Change and the Esophagus: Speculations on Changing Disease Patterns as the World Warms.Current gastroenterology reports · 2023Review
- Impact of Climate Change on Eye Diseases and Associated Economical Costs.International journal of environmental research and public health · 2021Review
- Review
- Prevalence of CagA and antimicrobial sensitivity ofInfectious agents and cancer · 2018Article
- Contaminated water as a source of Helicobacter pylori infection: A review.Journal of advanced research · 2015Review
- Helicobacter pylori vs coronary heart disease - searching for connections.World journal of cardiology · 2015Article
- Friend and foe: factors influencing the movement of the bacterium Helicobacter pylori along the parasitism-mutualism continuum.Evolutionary applications · 2015Review
- The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro.PloS one · 2015Article
- Helicobacter pylori genetic diversity and gastro-duodenal diseases in Malaysia.Scientific reports · 2014Article
- Genomic characterization of a Helicobacter pylori isolate from a patient with gastric cancer in China.Gut pathogens · 2014Article
- Structure and function of the human skin microbiome.Trends in microbiology · 2013Review
- Phylogeographic origin of Helicobacter pylori determines host-adaptive responses upon coculture with gastric epithelial cells.Infection and immunity · 2013Article
- Association of smoking, alcohol and NSAIDs use with expression of cag A and cag T genes of Helicobacter pylori in salivary samples of asymptomatic subjects.Asian Pacific journal of tropical biomedicine · 2012Article
- Genomes of two chronological isolates (Helicobacter pylori 2017 and 2018) of the West African Helicobacter pylori strain 908 obtained from a single patient.Journal of bacteriology · 2011Article
- Genome of Helicobacter pylori strain 908.Journal of bacteriology · 2010Article
- Helicobacter pylori: a poor man's gut pathogen?Gut pathogens · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori is a well known inhabitant of human stomach which is linked to peptic ulcer disease and gastric adenocarcinoma. It was recently shown in several studies that H. pylori can be harnessed as a surrogate marker of human migration and that its population structure and stratification patterns exactly juxtapose to those of Homo sapiens. This is enough a testimony to convey that H. pylori may have coevolved with their host. Several protective effects of H. pylori colonization have been considered as evidence of a presumed symbiotic relationship. Contrary to this assumption is the presence of a strong virulence apparatus within H. pylori; why a co-evolved parasite would try inflicting its host with serious infection and even causing cancer? The answer is perhaps embedded in the evolutionary history of both the bacterium and the host. We discuss a hypothetical scenario wherein H. pylori may have acquired virulence genes from donors within its environment that varied with change in human history and ecology. The H. pylori genomes sequenced to date portray fairly high abundance of such laterally acquired genes which have no assigned functions but could be linked to inflammatory responses or other pathogenic attributes. Therefore, the powerful virulence properties and survival strategies of Helicobacter make it a seasoned pathogen; thus the efforts to portray it as a commensal or a (harmless) 'bacterial parasite' need rethinking.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.