ArticleNano letters2010
Whole genome expression analysis reveals differential effects of TiO2 nanotubes on vascular cells.
Article in Nano letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 72 citations in OpenAlex.
- Ti-15Zr-5.5Cu: A dental titanium alloy with robust antibacterial activity and superior corrosion resistance.iScience · 2026Article
- Nanotexture and crystal phase regulation for synergistic enhancement in re-endothelialization on medical pure titanium surface.Materials today. Bio · 2024Article
- Synergistic effect of hierarchical topographic structure on 3D-printed Titanium scaffold for enhanced coupling of osteogenesis and angiogenesis.Materials today. Bio · 2023Article
- Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy.APL bioengineering · 2021Review
- Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials.Scientific data · 2021Article
- Mixed oxide nanotubes in nanomedicine: A dead-end or a bridge to the future?Ceramics international · 2021Review
- Successful Reduction of Neointimal Hyperplasia on Stainless Steel Coronary Stents by Titania Nanotexturing.ACS omega · 2020Article
- Insights into the angiogenic effects of nanomaterials: mechanisms involved and potential applications.Journal of nanobiotechnology · 2020Review
- Nanosurfaces modulate the mechanism of peri-implant endosseous healing by regulating neovascular morphogenesis.Communications biology · 2018Article
- Improved in vitro angiogenic behavior on anodized titanium dioxide nanotubes.Journal of nanobiotechnology · 2017Article
- Nitinol-Based Nanotubular Arrays with Controlled Diameters Upregulate Human Vascular Cell ECM Production.ACS biomaterials science & engineering · 2016Article
- Nitinol-based nanotubular coatings for the modulation of human vascular cell function.Nano letters · 2014Article
- Facile Synthesis of Robust Free-Standing TiOJournal of applied electrochemistry · 2014Article
- Investigating surface topology and cyclic-RGD peptide functionalization on vascular endothelialization.Journal of biomedical materials research. Part A · 2014Article
- System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses.Toxicology and applied pharmacology · 2013Article
- New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics.Journal of toxicology and environmental health. Part B, Critical reviews · 2012Article
- Molecular control of TiO₂-NPs toxicity formation at predicted environmental relevant concentrations by Mn-SODs proteins.PloS one · 2012Article
- Balancing forces: architectural control of mechanotransduction.Nature reviews. Molecular cell biology · 2011Review
- Synergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction media.Biomacromolecules · 2010Article
- TiOInternational journal of nanomedicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The response of primary human endothelial (ECs) and vascular smooth muscle cells (VSMCs) to TiO2 nanotube arrays is studied through gene expression analysis. Microarrays revealed that nanotubes enhanced EC proliferation and motility, decreased VSMC proliferation, and decreased expression of molecules involved in inflammation and coagulation in both cell types. Networks generated from significantly affected genes suggest that cells may be sensing nanotopographical cues via pathways previously implicated in sensing shear stress.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.