ReviewCellular & molecular immunology2010
Experimental evidence on the immunopathogenesis of primary biliary cirrhosis.
Review in Cellular & molecular immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 62 citations in OpenAlex.
- Combined treatment of budesonide and ursodeoxycholic acid for non-cirrhotic primary biliary cholangitis: a systematic review and meta-analysis.Hepatobiliary surgery and nutrition · 2026Article
- The impact of male sex on outcomes in primary biliary cholangitis.Scientific reports · 2026Article
- miRNA-21, an Important Regulator of Autoimmune Diseases.Current molecular medicine · 2025Review
- Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis.Arthritis research & therapy · 2023Article
- The latest research trends in primary biliary cholangitis: a bibliometric analysis.Clinical and experimental medicine · 2023Article
- Primary Biliary Cholangitis: Promising Emerging Innovative Therapies and Their Impact on GLOBE Scores.Hepatic medicine : evidence and research · 2023Review
- The Microbiome in Autoimmune Liver Diseases: Metagenomic and Metabolomic Changes.Frontiers in physiology · 2021Review
- Liver-resident NK cells suppress autoimmune cholangitis and limit the proliferation of CD4Cellular & molecular immunology · 2020Article
- Promoter hypermethylation of theJHEP reports : innovation in hepatology · 2019Article
- Autoreactive monoclonal antibodies from patients with primary biliary cholangitis recognize environmental xenobiotics.Hepatology (Baltimore, Md.) · 2017Article
- Expression of antisense of microRNA-26a-5p in mesenchymal stem cells increases their therapeutic effects against cirrhosis.American journal of translational research · 2017Article
- Primary biliary cirrhosis associated with Graves' disease in a male patient.Clinical journal of gastroenterology · 2016Article
- Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis.Journal of autoimmunity · 2015Article
- Primary biliary cirrhosis is a generalized autoimmune epithelitis.International journal of molecular sciences · 2015Review
- Expert panel workshop consensus statement on the role of the environment in the development of autoimmune disease.International journal of molecular sciences · 2014Review
- Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis.Auto- immunity highlights · 2013Article
- Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis.Hepatology (Baltimore, Md.) · 2012Article
- Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature.BMC gastroenterology · 2012Review
- Autoimmunity and environment: am I at risk?Clinical reviews in allergy & immunology · 2012Review
- Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22.Auto- immunity highlights · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease for which an autoimmune pathogenesis is supported by clinical and experimental data, including the presence of autoantibodies and autoreactive T cells. The etiology remains to be determined, yet data suggest that both a susceptible genetic background and unknown environmental factors determine disease onset. Multiple infectious and chemical candidates have been proposed to trigger the disease in a genetically susceptible host, mostly by molecular mimicry. Most recently, several murine models have been reported, including genetically determined models as well as models induced by immunization with xenobiotics and bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.