ArticleEuropean journal of human genetics : EJHG2010
Complete mitochondrial DNA sequences provide new insights into the Polynesian motif and the peopling of Madagascar.
Article in European journal of human genetics : EJHG, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed.
- Leveraging known Pacific colonisation times to test models for the ancestry of Southeast Asians.Scientific reports · 2025Article
- Ethnic Markers without Ethnic Conflict : Why do Interdependent Masikoro, Mikea, and Vezo of Madagascar Signal their Ethnic Differences?Human nature (Hawthorne, N.Y.) · 2021Article
- Dialects of Madagascar.PloS one · 2020Article
- Evidence of Austronesian Genetic Lineages in East Africa and South Arabia: Complex Dispersal from Madagascar and Southeast Asia.Genome biology and evolution · 2019Article
- Human phylogeography and diversity.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Contrasting Linguistic and Genetic Origins of the Asian Source Populations of Malagasy.Scientific reports · 2016Article
- Mitochondrial DNA and the Y chromosome suggest the settlement of Madagascar by Indonesian sea nomad populations.BMC genomics · 2015Article
- Human settlement history between Sunda and Sahul: a focus on East Timor (Timor-Leste) and the Pleistocenic mtDNA diversity.BMC genomics · 2015Article
- Taiwan Y-chromosomal DNA variation and its relationship with Island Southeast Asia.BMC genetics · 2014Article
- Maternal history of Oceania from complete mtDNA genomes: contrasting ancient diversity with recent homogenization due to the Austronesian expansion.American journal of human genetics · 2014Article
- Genome-wide evidence of Austronesian-Bantu admixture and cultural reversion in a hunter-gatherer group of Madagascar.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Multiple ethnic origins of mitochondrial DNA lineages for the population of Mauritius.PloS one · 2014Article
- Determination of population origin: a comparison of autosomal SNPs, Y-chromosomal and mtDNA haplogroups using a Malagasy population as example.European journal of human genetics : EJHG · 2013Article
- Identification of Polynesian mtDNA haplogroups in remains of Botocudo Amerindians from Brazil.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- A highly unstable recent mutation in human mtDNA.American journal of human genetics · 2013Article
- Tracing Arab-Islamic inheritance in Madagascar: study of the Y-chromosome and mitochondrial DNA in the Antemoro.PloS one · 2013Article
- Complete mitochondrial DNA genome sequences from the first New Zealanders.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- A small cohort of Island Southeast Asian women founded Madagascar.Proceedings. Biological sciences · 2012Article
- Complete mitochondrial DNA analysis of eastern Eurasian haplogroups rarely found in populations of northern Asia and eastern Europe.PloS one · 2012Article
- The origins and genetic distinctiveness of the Chamorros of the Marianas Islands: an mtDNA perspective.American journal of human biology : the official journal of the Human Biology CouncilArticle
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10 authors.
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Abstract
More than a decade of mitochondrial DNA (mtDNA) studies have given the 'Polynesian motif' renowned status as a marker for tracing the late-Holocene expansion of Austronesian speaking populations. Despite considerable research on the Polynesian motif in Oceania, there has been little equivalent work on the western edge of its expansion - leaving major issues unresolved regarding the motif's evolutionary history. This has also led to considerable uncertainty regarding the settlement of Madagascar. In this study, we assess mtDNA variation in 266 individuals from three Malagasy ethnic groups: the Mikea, Vezo, and Merina. Complete mtDNA genome sequencing reveals a new variant of the Polynesian motif in Madagascar; two coding region mutations define a Malagasy-specific sub-branch. This newly defined 'Malagasy motif' occurs at high frequency in all three ethnic groups (13-50%), and its phylogenetic position, geographic distribution, and estimated age all support a recent origin, but without conclusively identifying a specific source region. Nevertheless, the haplotype's limited diversity, similar to those of other mtDNA haplogroups found in our Malagasy groups, best supports a small number of initial settlers arriving to Madagascar through the same migratory process. Finally, the discovery of this lineage provides a set of new polymorphic positions to help localize the Austronesian ancestors of the Malagasy, as well as uncover the origin and evolution of the Polynesian motif itself.
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