ArticleGenetics2010
Regulation by blue light of the fluffy gene encoding a major regulator of conidiation in Neurospora crassa.
Article in Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- How fungi see the world: fungal photoreceptors and their role in the regulation of fungal biology.Microbiology and molecular biology reviews : MMBR · 2025Review
- Blue Light Receptor WC-2 Regulates Ganoderic Acid Biosynthesis inJournal of fungi (Basel, Switzerland) · 2025Article
- Article
- Construction of Light-Responsive Gene Regulatory Network for Growth, Development and Secondary Metabolite Production inBiology · 2022Article
- Article
- A global search for novel transcription factors impacting the Neurospora crassa circadian clock.G3 (Bethesda, Md.) · 2021Article
- Light Intensity Alters the Behavior ofFrontiers in plant science · 2021Article
- Wild Isolates ofMicroorganisms · 2020Article
- Article
- Expression of putative circadian clock components in the arbuscular mycorrhizal fungus Rhizoglomus irregulare.Mycorrhiza · 2018Article
- Light sensing by opsins and fungal ecology: NOP-1 modulates entry into sexual reproduction in response to environmental cues.Molecular ecology · 2018Article
- Regulation of conidiation in Botrytis cinerea involves the light-responsive transcriptional regulators BcLTF3 and BcREG1.Current genetics · 2017Article
- Fungal Histidine Phosphotransferase Plays a Crucial Role in Photomorphogenesis and Pathogenesis inFrontiers in chemistry · 2017Article
- Pre-mRNA splicing is modulated by antifungal drugs in the filamentous fungus Neurospora crassa.FEBS open bio · 2016Article
- Genome-wide characterization of light-regulated genes in Neurospora crassa.G3 (Bethesda, Md.) · 2014Article
- Alteration of light-dependent gene regulation by the absence of the RCO-1/RCM-1 repressor complex in the fungus Neurospora crassa.PloS one · 2014Article
- The Uve1 endonuclease is regulated by the white collar complex to protect cryptococcus neoformans from UV damage.PLoS genetics · 2013Article
- Article
- BcAtf1, a global regulator, controls various differentiation processes and phytotoxin production in Botrytis cinerea.Molecular plant pathology · 2012Article
- Regulation of conidiation by light in Aspergillus nidulans.Genetics · 2011Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of asexual spores, that is, the process of conidiation, in the fungus Neurospora crassa is increased by light. The fluffy (fl) gene, encoding a major regulator of conidiation, is activated by light. We describe here a detailed characterization of the regulation by blue light of fl in vegetative hyphae. This induction requires the white collar complex (WCC) while the FLD protein acts as a dark repressor of fl transcription. We show that the WCC directly regulates fl transcription in response to blue light after transiently binding the promoter. We propose that fl is repressed by FLD in vegetative mycelia and that the repression is lost after light exposure and WCC activation. The increase in fl mRNA in vegetative mycelia after light exposure, and the corresponding increase in the amount of the regulatory FL protein, should promote the activation of the conidiation pathway. The activation by light of fl provides a simple mechanism for the activation of conidiation by blue light in Neurospora that may be at work in other fungi.
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