Evidence map›Paper›PMID 20025755›Full record

ArticleEnvironmental health : a global access science source2009

Fine particulate air pollution and its components in association with cause-specific emergency admissions.

Antonella Zanobetti, Meredith Franklin, Petros Koutrakis, Joel Schwartz

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Environmental health : a global access science source, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 202 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed, 7 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

202 citing papers in PubMed, 7 syntheses or guidelines pooled it, 504 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Indoor/Outdoor Particulate Matter and Related Pollutants in a Sensitive Public Building in Madrid (Spain).International journal of environmental research and public health · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. PMInternational journal of medical sciences · 2024
    Article
  20. Article

142 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Antonella ZanobettiDepartment of Environmental Health, School of Public Health, Harvard University, Boston, MA, USA. azanobet@hsph.harvard.edu
Meredith Franklin
Petros Koutrakis
Joel Schwartz
Boston University · USHarvard University · USUniversity of Chicago · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
NIEHS NIH HHS P30 ES000002PHS HHS NIEHS 00002
6 · The paper itself

Abstract

backgroundAlthough the association between exposure to particulate matter and health is well established, there remains uncertainty as to whether certain chemical components are more harmful than others. We explored whether the association between cause-specific hospital admissions and PM(2.5) was modified by PM(2.5) chemical composition.

methodsWe estimated the association between daily PM(2.5) and emergency hospital admissions for cardiac causes (CVD), myocardial infarction (MI), congestive heart failure (CHF), respiratory disease, and diabetes in 26 US communities, for the years 2000-2003. Using meta-regression, we examined how this association was modified by season- and community-specific PM(2.5) composition, controlling for seasonal temperature as a surrogate for ventilation.

resultsFor a 10 microg/m3 increase in 2-day averaged PM(2.5) concentration we found an increase of 1.89% (95% CI: 1.34- 2.45) in CVD, 2.25% (95% CI: 1.10- 3.42) in MI, 1.85% (95% CI: 1.19- 2.51) in CHF, 2.74% (95% CI: 1.30- 4.2) in diabetes, and 2.07% (95% CI: 1.20- 2.95) in respiratory admissions. The association between PM2.5 and CVD admissions was significantly modified when the mass was high in Br, Cr, Ni, and Na(+), while mass high in As, Cr, Mn, OC, Ni, and Na(+) modified MI, and mass high in As, OC, and SO(4)(2-) modified diabetes admissions. For these species, an interquartile range increase in their relative proportion was associated with a 1-2% additional increase in daily admissions per 10 microg/m(3) increase in mass.

conclusionsWe found that PM(2.5) mass higher in Ni, As, and Cr, as well as Br and OC significantly increased its effect on hospital admissions. This result suggests that particles from industrial combustion sources and traffic may, on average, have greater toxicity.

Indexed as

HospitalizationVehicle EmissionsAgedAir PollutionCardiovascular DiseasesDiabetes MellitusEnvironmental ExposureHumansParticulate MatterRespiratory Tract DiseasesTemperatureUnited StatesUrban PopulationParticulate MatterVehicle Emissions

Identifiers

PMID20025755
PMCPMC2807856
OpenAlexW1978883267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.