ArticleJournal of experimental & clinical cancer research : CR2009
Subjective versus objective risk in genetic counseling for hereditary breast and/or ovarian cancers.
Article in Journal of experimental & clinical cancer research : CR, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Impact of delivery models on understanding genomic risk for type 2 diabetes.Public health genomics · 2014Trial
- Correlates of family health history discussions between college students and physicians: does family cancer history make a difference?The journal of primary prevention · 2011Trial
- Breast/ovarian cancer genetic counseling: Do anxiety, depression, and health care-related fears influence cancer worry and risk perception?Cancer medicine · 2023Article
- Breast cancer awareness among women in the Syrian Coast: a cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- BRCA1/2 pathogenetic variant carriers and reproductive decisions: Gender differences and factors associated with the choice of preimplantation genetic diagnosis (PGD) and prenatal diagnosis (PND).Journal of assisted reproduction and genetics · 2022Review
- Expectations and psychological issues before genetic counseling: analysis of distress determinant factors.Hereditary cancer in clinical practice · 2020Article
- What does risk of future cancer mean to breast cancer patients?Breast cancer research and treatment · 2019Article
- Relationship between individual and family characteristics and psychosocial factors in persons with familial pancreatic cancer.Psycho-oncology · 2018Article
- Explanatory Models of Genetics and Genetic Risk among a Selected Group of Students.Frontiers in public health · 2016Article
- Intuition versus cognition: a qualitative exploration of how women understand and manage their increased breast cancer risk.Journal of behavioral medicine · 2015Article
- Characteristics associated with genetic counseling referral and BRCA1/2 testing among women in a large integrated health system.Genetics in medicine : official journal of the American College of Medical Genetics · 2015Article
- Illness perceptions, risk perception and worry in SDH mutation carriers.Familial cancer · 2014Article
- Comparison of the screening practices of unaffected noncarriers under 40 and between 40 and 49 in BRCA1/2 families.Journal of genetic counseling · 2013Article
- Family history of cancer and its association with breast cancer risk perception and repeat mammography.American journal of public health · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the fact that genetic counseling in oncology provides information regarding objective risks, it can be found a contrast between the subjective and objective risk. The aims of this study were to evaluate the accuracy of the perceived risk compared to the objective risk estimated by the BRCApro computer model and to evaluate any associations between medical, demographic and psychological variables and the accuracy of risk perception.
methods130 subjects were given medical-demographic file, Cancer and Genetic Risk Perception, Hospital Anxiety-Depression Scale. It was also computed an objective evaluation of the risk by the BRCApro model.
resultsThe subjective risk was significantly higher than objective risk. The risk of tumour was overestimated by 56%, and the genetic risk by 67%. The subjects with less cancer affected relatives significantly overestimated their risk of being mutation carriers and made a more inaccurate estimation than high risk subjects.
conclusionThe description of this sample shows: general overestimation of the risk, inaccurate perception compared to BRCApro calculation and a more accurate estimation in those subjects with more cancer affected relatives (high risk subjects). No correlation was found between the levels of perception of risk and anxiety and depression. Based on our findings, it is worth pursuing improved communication strategies about the actual cancer and genetic risk, especially for subjects at "intermediate and slightly increased risk" of developing an hereditary breast and/or ovarian cancer or of being mutation carrier.
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