ArticleNanomedicine (London, England)2010
Programmable nano-bio-chips: multifunctional clinical tools for use at the point-of-care.
Article in Nanomedicine (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma--a systematic review.Head & face medicine · 2015Pooled it
- A Cell Culture Chip with Transparent, Micropillar-Decorated Bottom for Live Cell Imaging and Screening of Breast Cancer Cells.Micromachines · 2022Article
- Sensors that Learn: The Evolution from Taste Fingerprints to Patterns of Early Disease Detection.Micromachines · 2019Review
- Metabolomics as a Driver in Advancing Precision Medicine in Sepsis.Pharmacotherapy · 2017Review
- Innovative Programmable Bio-Nano-Chip Digitizes Biology Using Sensors That Learn Bridging Biomarker Discovery and Clinical Implementation.Frontiers in public health · 2017Review
- Cardiac ScoreCard: A Diagnostic Multivariate Index Assay System for Predicting a Spectrum of Cardiovascular Disease.Expert systems with applications · 2016Article
- Challenges and opportunities for translating medical microdevices: insights from the programmable bio-nano-chip.Bioanalysis · 2016Article
- Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.Lab on a chip · 2015Article
- Programmable bio-nano-chip system: a flexible diagnostic platform that learns.Journal of biosensors & bioelectronics · 2015Article
- On the Slow Diffusion of Point-of-Care Systems in Therapeutic Drug Monitoring.Frontiers in bioengineering and biotechnology · 2015Review
- Article
- Future Imaging Alternatives: The Clinical Non-invasive Modalities in Diagnosis of Oral Squamous Cell Carcinoma (OSCC).The open dentistry journal · 2015Article
- Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array.Lab on a chip · 2013Article
- Optical imaging techniques for point-of-care diagnostics.Lab on a chip · 2013Review
- Porous bead-based diagnostic platforms: bridging the gaps in healthcare.Sensors (Basel, Switzerland) · 2012Review
- Programmable bio-nano-chip systems for serum CA125 quantification: toward ovarian cancer diagnostics at the point-of-care.Cancer prevention research (Philadelphia, Pa.) · 2012Article
- Translational and clinical applications of salivary diagnostics.Advances in dental research · 2011Article
- Location of biomarkers and reagents within agarose beads of a programmable bio-nano-chip.Small (Weinheim an der Bergstrasse, Germany) · 2011Article
- Miniaturized lensless imaging systems for cell and microorganism visualization in point-of-care testing.Biotechnology journal · 2011Review
- Current development of saliva/oral fluid-based diagnostics.Texas dental journal · 2010Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
A new generation of programmable diagnostic devices is needed to take advantage of information generated from the study of genomics, proteomics, metabolomics and glycomics. This report describes the 'programmable nano-bio-chip' with potential to bridge the significant scientific, technology and clinical gaps through the creation of a diagnostic platform to measure the molecules of life. This approach, with results at the point-of-care, possesses capabilities for measuring such diverse analyte classes as cells, proteins, DNA and small molecules in the same compact device. Applications such as disease diagnosis and prognosis for areas including cancer, heart disease and HIV are described. New diagnostic panels are inserted as 'plug and play' elements into the modular platform with universal assay operating systems and standard read out sequences. The nano-bio-chip ensemble exhibits excellent analytical performance and cost-effectiveness with extensive validation versus standard reference methods (R(2) = 0.95-0.99). This report describes the construction and use of two major classes of nano-bio-chip designs that serve as cellular and chemical processing units, and provides perspective on future growth in this newly emerging field of programmable nano-bio-chip sensor systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.