ArticleNanomedicine (London, England)2010
Shape-coded silica nanotubes for multiplexed bioassay: rapid and reliable magnetic decoding protocols.
Article in Nanomedicine (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Nanoporous Anodic Alumina Photonic Crystals for Optical Chemo- and Biosensing: Fundamentals, Advances, and Perspectives.Nanomaterials (Basel, Switzerland) · 2018Review
- Nanostructural Engineering of Nanoporous Anodic Alumina for Biosensing Applications.Materials (Basel, Switzerland) · 2014Review
- Nanoporous anodic alumina platforms: engineered surface chemistry and structure for optical sensing applications.Sensors (Basel, Switzerland) · 2014Review
- Nanodetoxification: emerging role of nanomaterials in drug intoxication treatment.Nanomedicine (London, England) · 2011Article
- Experimental considerations on the cytotoxicity of nanoparticles.Nanomedicine (London, England) · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
aimsThe recent development of 1D barcode arrays has proved their capabilities to be applicable to highly multiplexed bioassays. This article introduces two magnetic decoding protocols for suspension arrays of shape-coded silica nanotubes to process multiplexed assays rapidly and easily, which will benefit the minimization and automation of the arrays.
methodsIn the first protocol, the magnetic nanocrystals are incorporated into the inner voids of barcoded silica nanotubes in order to give the nanotubes magnetic properties. The second protocol is performed by trapping the barcoded silica nanotubes onto streptavidin-modified magnetic beads.
resultsThe rapid and easy decoding process was demonstrated by applying the above two protocols to multiplexed assays, resulting in high selectivity. Furthermore, the magnetic bead-trapped barcode nanotubes provided a great opportunity to exclude the use of dye molecules in multiplexed assays by using barcode nanotubes as signals.
conclusionThe rapid and easy manipulation of encoded carriers using magnetic properties could be used to develop promising suspension arrays for portable bioassays.
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Registered trials
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