Evidence map›Paper›PMID 20025024›Full record

ReviewNeurourology and urodynamics2010

Neural control of the lower urinary tract: peripheral and spinal mechanisms.

L Birder, W de Groat, I Mills, J Morrison, K Thor, M Drake

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 78 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02232282 nacompletednot on this mapstarted 2014, after this paper: background citation

Acupuncture for Female Interstitial Cystitis/Painful Bladder Syndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial

TypeinterventionalSponsorLoyola UniversityRan2014 to 2017Enrolled22ConditionsPainful Bladder Syndrome, Interstitial CystitisArmsstandard acupuncture treatment, Control Sham/Minimal Acupuncture
NCT02517996 naterminatednot on this mapstarted 2015, after this paper: background citation

Use of Preemptive Pudendal Nerve Block Prior to Hydrodistension for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-blinded, Randomized Control Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2015 to 2018Enrolled18ConditionsInterstitial Cystitis, Painful Bladder SyndromeArmsLidocaine, Placebo
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 2 syntheses or guidelines pooled it, 169 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Sprouting of afferent and efferent inputs to pelvic organs after spinal cord injury.Journal of neuropathology and experimental neurology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Real-Time Void Spot Assay.Journal of visualized experiments : JoVE · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

L BirderDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. lbirder@pitt.edu
W de Groat
I Mills
J Morrison
K Thor
M Drake
University of Pittsburgh · USPfizer (United Kingdom) · GBSouthmead Hospital · GBUniversity of Leeds · GB

Funding

ROLE OF NITRIC OXIDE IN INTERSTITIAL CYSTITISR01DK057284 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A · 2000 to 2014
$4.3M
Nitric Oxide in Bladder Neural-Epithelial SignalingR37DK054824 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A · 2007 to 2016
$3.0M
NIDDK NIH HHS R01 DK057284NIDDK NIH HHS R37 DK054824
6 · The paper itself

Abstract

This review deals with individual components regulating the neural control of the urinary bladder. This article will focus on factors and processes involved in the two modes of operation of the bladder: storage and elimination. Topics included in this review include: (1) The urothelium and its roles in sensor and transducer functions including interactions with other cell types within the bladder wall ("sensory web"), (2) The location and properties of bladder afferents including factors involved in regulating afferent sensitization, (3) The neural control of the pelvic floor muscle and pharmacology of urethral and anal sphincters (focusing on monoamine pathways), (4) Efferent pathways to the urinary bladder, and (5) Abnormalities in bladder function including mechanisms underlying comorbid disorders associated with bladder pain syndrome and incontinence.

Indexed as

Mechanotransduction, CellularSensationAfferent PathwaysAnal CanalAnimalsCystitis, InterstitialEfferent PathwaysFemaleHumansMaleNerve Growth FactorPelvic FloorPeripheral Nervous SystemSodium ChannelsSpinal NervesUrethraNerve Growth FactorSodium Channels

Identifiers

PMID20025024
PMCPMC2910109
OpenAlexW2003033531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.