Evidence map›Paper›PMID 20022675›Full record

ArticleNeurobiology of aging2011

Age-related reorganization of functional networks for successful conflict resolution: a combined functional and structural MRI study.

Tilman Schulte, Eva M Müller-Oehring, Sandra Chanraud, Margaret J Rosenbloom, Adolf Pfefferbaum, Edith V Sullivan

Abstract read
In one paragraph

Article in Neurobiology of aging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tilman SchulteNeuroscience Program, SRI International, Menlo Park, CA 94025, USA.
Eva M Müller-Oehring
Sandra Chanraud
Margaret J Rosenbloom
Adolf Pfefferbaum
Edith V Sullivan

Funding

CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR01AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF, ZAHR, NATALIE M · 1985 to 2025
$13.0M
CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISMR01AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI, ZAHR, NATALIE M · 1996 to 2025
$8.3M
Cerebellar Structure and Function in AlcoholismR37AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2010 to 2019
$5.4M
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR37AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF · 1996 to 2005
$4.4M
NORMAL AGING OF BRAIN STRUCTURE AND FUNCTIONR01AG017919 · NIA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2000 to 2010
$3.9M
Translational Studies of Brain Circuitry Disrupted by AlcoholismK05AA017168 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2008 to 2017
$2.2M
Neural Correlates of Implicit Processes of Attention & Emotion in AlcoholismR01AA018022 · NIAAA · SRI INTERNATIONAL · PI SCHULTE, TILMAN · 2008 to 2012
$2.1M
International Research Collaboration on Neuroimaging Studies of AlcoholismR01AA017923 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF, SULLIVAN, EDITH VIONI · 2018 to 2019
$496k
NIAAA NIH HHS AA005965NIAAA NIH HHS AA010723NIAAA NIH HHS AA017168NIAAA NIH HHS K05 AA017168NIAAA NIH HHS R01 AA005965NIAAA NIH HHS R01 AA010723NIAAA NIH HHS R01 AA017923NIAAA NIH HHS R01 AA018022NIAAA NIH HHS R37 AA005965NIAAA NIH HHS R37 AA010723NIA NIH HHS AG017919NIA NIH HHS R01 AG017919
6 · The paper itself

Abstract

Aging has readily observable effects on the ability to resolve conflict between competing stimulus attributes that are likely related to selective structural and functional brain changes. To identify age-related differences in neural circuits subserving conflict processing, we combined structural and functional MRI and a Stroop Match-to-Sample task involving perceptual cueing and repetition to modulate resources in healthy young and older adults. In our Stroop Match-to-Sample task, older adults handled conflict by activating a frontoparietal attention system more than young adults and engaged a visuomotor network more than young adults when processing repetitive conflict and when processing conflict following valid perceptual cueing. By contrast, young adults activated frontal regions more than older adults when processing conflict with perceptual cueing. These differential activation patterns were not correlated with regional gray matter volume despite smaller volumes in older than young adults. Given comparable performance in speed and accuracy of responding between both groups, these data suggest that successful aging is associated with functional reorganization of neural systems to accommodate functionally increasing task demands on perceptual and attentional operations.

Indexed as

Conflict, PsychologicalAdultAgedAged, 80 and overAgingAttentionBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNerve NetNeuropsychological TestsOrgan Size

Identifiers

PMID20022675
PMCPMC2888896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.