Evidence map›Paper›PMID 20020675›Full record

ArticleAnalytical chemistry2009

Fabrication and characterization of DNA arrays prepared on carbon-on-metal substrates.

Matthew R Lockett, Lloyd M Smith

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Carbon Substrates: A Stable Foundation for Biomolecular Arrays.Annual review of analytical chemistry (Palo Alto, Calif.) · 2015
    Review
  3. Article
  4. RNA-mediated gene assembly from DNA arrays.Angewandte Chemie (International ed. in English) · 2012
    Article
  5. In situ Synthesis of Oligonucleotide Arrays on Surfaces Coated with Crosslinked Polymer Multilayers.Chemistry of materials : a publication of the American Chemical Society · 2012
    Article
  6. Review
  7. The Formation and Stability of Alkylthiol Monolayers on Carbon Substrates.The journal of physical chemistry. C, Nanomaterials and interfaces · 2010
    Article
  8. Minimal size of coffee ring structure.The journal of physical chemistry. B · 2010
    Article
  9. Article
  10. Photopatterned thiol surfaces for biomolecule immobilization.Langmuir : the ACS journal of surfaces and colloids · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew R LockettDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Lloyd M Smith
University of Wisconsin–Madison · US

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
SNP Analysis by Surface Invasive Cleavage on DNA ArraysR01HG002298 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI SMITH, LLOYD M · 2001 to 2007
$2.7M
NHGRI NIH HHS R01 HG002298NHGRI NIH HHS R01HG002298NIGMS NIH HHS 5T32GM08349NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

Carbon-on-metal substrates consist of a surface plasmon-conducting metal substrate with a thin amorphous carbon overlayer. Recently, oligonucleotide arrays were in situ synthesized on carbon-on-gold substrates, and DNA hybridization experiments were monitored with surface plasmon resonance (SPR) imaging. We describe here the thorough characterization of these substrates and arrays as they progress through the fabrication process. Two surface plasmon-conducting metals, gold and silver, were utilized in the carbon-on-metal substrate preparation and their SPR responses compared. Oligonucleotide arrays synthesized on the carbon-on-metal substrates were analyzed with fluorescence- and SPR-based measurements. The stability of the carbon-on-metal substrates when exposed to prolonged incubations and/or serial hybridizations was also determined.

Indexed as

Oligonucleotide Array Sequence AnalysisSurface Plasmon ResonanceBiosensing TechniquesCarbonDNAGoldMetal NanoparticlesSilverSurface PropertiesCarbonDNAGoldSilver

Identifiers

PMID20020675
PMCPMC2797128
OpenAlexW1995498672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.