ArticleInternational urology and nephrology2010
Late diagnosis of primary hyperoxaluria after failed kidney transplantation.
Article in International urology and nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Clinical and Histopathologic Spectrum of Primary Nonfunction in Renal Allografts.Kidney international reports · 2026Article
- Case series and literature review of primary hyperoxaluria type 1 in Chinese patients.Urolithiasis · 2023Article
- Article
- [Nephrolithiasis and nephrocalcinosis in children and adolescents].Urologie (Heidelberg, Germany) · 2022Review
- Primary hyperoxaluria diagnosed after kidney transplant: A review of the literature and case report of aggressive renal replacement therapy and lumasiran to prevent allograft loss.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Review
- Primary hyperoxaluria diagnosed after kidney transplantation: a case report and literature review.BMC nephrology · 2021Review
- Integration of exome sequencing and metabolic evaluation for the diagnosis of children with urolithiasis.World journal of urology · 2021Article
- The association of calcium oxalate deposition in kidney allografts with graft and patient survival.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Primary hyperoxaluria diagnosed after kidney transplantation failure: lesson from 3 case reports and literature review.BMC nephrology · 2019Review
- Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression.JAMA internal medicine · 2019Observational
- Primary hyperoxaluria in populations of Pakistan origin: results from a literature review and two major registries.Urolithiasis · 2018Review
- Identification of compound heterozygous patients with primary hyperoxaluria type 1: clinical evaluations and in silico investigations.BMC nephrology · 2017Article
- Unusual clinical outcome of primary Hyperoxaluria type 1 in Tunisian patients carrying 33_34InsC mutation.BMC nephrology · 2017Article
- Acute oxalate nephropathy following kidney transplantation: Report of three cases.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Primary and secondary hyperoxaluria: Understanding the enigma.World journal of nephrology · 2015Review
- Primary hyperoxaluria type 1: practical and ethical issues.Pediatric nephrology (Berlin, Germany) · 2013Review
- Current medical treatment in pediatric urolithiasis.Turkish journal of urology · 2013Review
- Urolithiasis in children: medical approach.Pediatric clinics of North America · 2012Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive inborn error of the glyoxylate metabolism that is based on absence, deficiency or mislocalization of the liver-specific peroxisomal enzyme alanine:glyoxylate aminotransferase. Hyperoxaluria leads to recurrent formation of calculi and/or nephrocalcinosis and often early end-stage renal disease (ESRD) accompanied by systemic calcium oxalate crystal deposition. In this report, we describe an adult female patient with only one stone passage before development of ESRD. With unknown diagnosis of PH, the patient received an isolated kidney graft and developed an early onset of graft failure. Although initially presumed as an acute rejection, the biopsy revealed calcium oxalate crystals, which then raised a suspicion of primary hyperoxaluria. The diagnosis was later confirmed by hyperoxaluria, elevated plasma oxalate levels and mutation of the AGXT gene, showing the patient to be compound heterozygous for the c.33_34InsC and c.508G > A mutations. Plasma oxalate levels did not decrease after high-dose pyridoxine treatment. Based on this case report, we would recommend in all patients even with a minor history of nephrolithiasis but progression to chronic renal failure to exclude primary hyperoxaluria before isolated kidney transplantation is considered.
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