Evidence map›Paper›PMID 20019911›Full record

ArticleEnvironmental health perspectives2009

Predictors of serum dioxins and PCBs among peripubertal Russian boys.

Jane S Burns, Paige L Williams, Oleg Sergeyev, Susan Korrick, Mary M Lee, Boris Revich, Larisa Altshul, Donald G Patterson, Wayman E Turner, Larry L Needham and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

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  17. The spatial distribution of human exposure to PCBs around a former production site in Slovakia.Environmental science and pollution research international · 2015
    Article
  18. The 12th International HCH and Pesticides Forum in Kiev/Ukraine.Environmental science and pollution research international · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 4 countries.

Jane S BurnsEnvironmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA. jburns@hsph.harvard.edu
Paige L Williams
Oleg Sergeyev
Susan Korrick
Mary M Lee
Boris Revich
Larisa Altshul
Donald G Patterson
Wayman E Turner
Larry L Needham
Igor Saharov
Russ Hauser
Centers for Disease Control and Prevention · USBrigham and Women's Hospital · USEnvironmental Health · GBHarvard University · USHarvard University Press · USInstitute of Economic Forecasting · RUInstitute of Forensic Science · CNNational Medical Research Center for Hematology · RUSamara State Medical University · RUUniversity of Massachusetts Chan Medical School · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Effects of Environmental Phthalates and Chemical Mixtures on Male Puberty and Semen QualityR01ES014370 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HAUSER, RUSS B · 2006 to 2021
$8.2M
NIEHS NIH HHS 5T32-ES07069-28NIEHS NIH HHS ES00002NIEHS NIH HHS ES014370NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES014370NIEHS NIH HHS T32 ES007069
6 · The paper itself

Abstract

backgroundAlthough sources and routes of exposure to dioxins and polychlorinated biphenyls (PCBs) have been studied, information regarding exposure among children is limited. Breast-feeding and diet are two important contributors to early life exposure. To further understand other significant contributors to childhood exposure, we studied a cohort of children from a city with high environmental dioxin levels.

objectivesWe investigated predictors of serum concentrations of polychlorinated dibenzo-p-dioxins (PCDDs)/polychlorinated dibenzofurans (PCDFs)/co-planar PCBs (C-PCBs), toxic equivalents (TEQs), and PCBs among 8- to 9-year-old boys in Chapaevsk, Russia.

methodsWe used general linear regression models to explore associations of log(10)-transformed serum concentrations of PCDDs/PCDFs/C-PCBs, TEQs, and PCBs at study entry with anthropometric, demographic, geographic, and dietary factors in 482 boys in Chapaevsk, Russia.

resultsThe median (25th, 75th percentile) concentration for total 2005 TEQs was 21.1 pg/g lipid (14.4, 33.2). Boys who were older, consumed local foods, were breast-fed longer, and whose mothers were employed at the Khimprom chemical plant (where chlorinated chemicals were produced) or gardened locally had significantly higher serum dioxins and PCBs, whereas boys with higher body mass index or more educated parents had significantly lower serum dioxins and PCBs. Boys who lived < 2 km from Khimprom had higher total TEQs (picograms per gram lipid) [adjusted mean = 30.6; 95% confidence interval (CI), 26.8-35.0] than boys who lived > 5 km away (adjusted mean = 18.8; 95% CI, 17.2-20.6).

conclusionsOur findings suggest that there are specific local sources of dioxin and PCB exposure among children in Chapaevsk including maternal gardening, consumption of locally grown food, and residential proximity to the Khimprom plant.

Indexed as

BenzofuransChildDibenzofurans, PolychlorinatedDioxinsEnvironmental PollutantsHumansLinear ModelsMalePolychlorinated BiphenylsPolychlorinated DibenzodioxinsPubertyRisk FactorsRussiaBenzofuransDibenzofurans, PolychlorinatedDioxinsEnvironmental PollutantsPolychlorinated BiphenylsPolychlorinated Dibenzodioxinschildrendietenvironmentepidemiologypolychlorinated biphenylspolychlorinated dibenzodioxinspolychlorinated dibenzofurans

Identifiers

PMID20019911
PMCPMC2790515
OpenAlexW2043207314

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.