ArticleAmerican journal of public health2010
Estimating the risks and benefits of nicotine replacement therapy for smoking cessation in the United States.
Article in American journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- E-cigarettes and smoking cessation: evidence from a systematic review and meta-analysis.PloS one · 2015Pooled it
- Success rates with nicotine personal vaporizers: a prospective 6-month pilot study of smokers not intending to quit.BMC public health · 2014Trial
- Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation.Clinical proteomics · 2025Article
- Tobacco Smoking Prevalence, Health Risk, and Cessation in the UAE.Oman medical journal · 2020Review
- Experiences of women with cervical dysplasia and associated diagnoses using electronic cigarettes for smoking substitution.Health expectations : an international journal of public participation in health care and health policy · 2019Article
- Stillbirth Among Women Prescribed Nicotine Replacement Therapy in Pregnancy: Analysis of a Large UK Pregnancy Cohort.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Effectiveness and tolerability of electronic cigarette in real-life: a 24-month prospective observational study.Internal and emergency medicine · 2014Observational
- Article
- Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers.Molecular cancer research : MCR · 2014Review
- Population-based survey of cessation aids used by Swedish smokers.Harm reduction journal · 2012Article
- Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.Cancer prevention research (Philadelphia, Pa.) · 2011Article
- Nicotine aggravates the brain postischemic inflammatory response.American journal of physiology. Heart and circulatory physiology · 2011Article
- Nicotine replacement therapy for the palliation of nicotine abstinence syndrome: boon more than bane.Indian journal of palliative careArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare potential population-wide benefits and risks, we examined the potential impact of increased nicotine replacement therapy (NRT) use for smoking cessation on future US mortality.
methodsWe developed a simulation model incorporating a Monte Carlo uncertainty analysis, with data from the 2005 National Health Interview Survey and Cancer Prevention Study II. We estimated the number of avoided premature deaths from smoking attributable to increased NRT use, before and after incorporating assumptions about NRT harm.
resultsWe estimate that a gradual increase in the proportion of NRT-aided quit attempts to 100% by 2025 would lead to 40,000 (95% credible interval=31,000, 50,000) premature deaths avoided over a 20-year period. Most avoided deaths would be attributable to lung cancer and cardiovascular disease. After we incorporated assumptions about potential risk from long-term NRT, the estimate of avoided premature deaths from all causes declined to 32 000.
conclusionsEven after we assumed some harm from long-term NRT use, the benefits from increased cessation success far outweigh the risks. However, the projected reduction in premature mortality still reflects a small portion of the tobacco-related deaths expected over a 20-year period.
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