ArticleJournal of experimental botany2010
Plant cell division is specifically affected by nitrotyrosine.
Article in Journal of experimental botany, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
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- Switching cell fate by the actin-auxin oscillator in Taxus: cellular aspects of plant cell fermentation.Plant cell reports · 2022Article
- Insights into the Mechanisms of Heat Priming and Thermotolerance in Tobacco Pollen.International journal of molecular sciences · 2021Article
- Jasmonates, Ethylene and Brassinosteroids Control Adventitious and Lateral Rooting as Stress Avoidance Responses to Heavy Metals and Metalloids.Biomolecules · 2021Review
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- Flax tubulin and CesA superfamilies represent attractive and challenging targets for a variety of genome- and base-editing applications.Functional & integrative genomics · 2020Review
- Jasmonic Acid Methyl Ester Induces Xylogenesis and Modulates Auxin-Induced Xylary Cell Identity with NO Involvement.International journal of molecular sciences · 2019Article
- Posttranslational modification of plant microtubules.Plant signaling & behavior · 2019Article
- Salt-inducible expression of OsJAZ8 improves resilience against salt-stress.BMC plant biology · 2018Article
- Histological anomalies and alterations in enzyme activities of the earthworm Glyphidrillus tuberosus exposed to high concentrations of phosphogypsum.Environmental monitoring and assessment · 2018Article
- Grapevine fatty acid hydroperoxide lyase generates actin-disrupting volatiles and promotes defence-related cell death.Journal of experimental botany · 2018Article
- A rice class-XIV kinesin enters the nucleus in response to cold.Scientific reports · 2018Article
- Jasmonates are induced by the PAMP flg22 but not the cell death-inducing elicitor Harpin in Vitis rupestris.Protoplasma · 2017Article
- Protein Tyrosine Nitration during Development and Abiotic Stress Response in Plants.Frontiers in plant science · 2016Review
- Tubulin C-terminal Post-translational Modifications Do Not Occur in Wood Forming Tissue ofFrontiers in plant science · 2016Article
- Spatial and temporal regulation of the metabolism of reactive oxygen and nitrogen species during the early development of pepper (Capsicum annuum) seedlings.Annals of botany · 2015Article
- Suppression of tubulin detyrosination by parthenolide recruits the plant-specific kinesin KCH to cortical microtubules.Journal of experimental botany · 2015Article
- Nitrosative stress triggers microtubule reorganization in Arabidopsis thaliana.Journal of experimental botany · 2014Article
- Nanosecond electric pulses affect a plant-specific kinesin at the plasma membrane.The Journal of membrane biology · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Virtually all eukaryotic alpha-tubulins harbour a C-terminal tyrosine that can be reversibly removed and religated, catalysed by a specific tubulin-tyrosine carboxypeptidase (TTC) and a specific tubulin-tyrosine ligase (TTL), respectively. The biological function of this post-translational modification has remained enigmatic. 3-nitro-L-tyrosine (nitrotyrosine, NO(2)Tyr), can be incorporated into detyrosinated alpha-tubulin instead of tyrosine, producing irreversibly nitrotyrosinated alpha-tubulin. To gain insight into the possible function of detyrosination, the effect of NO(2)Tyr has been assessed in two plant model organisms (rice and tobacco). NO(2)Tyr causes a specific, sensitive, and dose-dependent inhibition of cell division that becomes detectable from 1 h after treatment and which is not observed with non-nitrosylated tyrosine. These effects are most pronounced in cycling tobacco BY-2 cells, where the inhibition of cell division is accompanied by a stimulation of cell length, and a misorientation of cross walls. NO(2)Tyr reduces the abundance of the detyrosinated form of alpha-tubulin whereas the tyrosinated alpha-tubulin is not affected. These findings are discussed with respect to a model where NO(2)Tyr is accepted as substrate by TTL and subsequently blocks TTC activity. The irreversibly tyrosinated alpha-tubulin impairs microtubular functions that are relevant to cell division in general, and cell wall deposition in particular.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.