ArticlePlant physiology2010
MEF9, an E-subclass pentatricopeptide repeat protein, is required for an RNA editing event in the nad7 transcript in mitochondria of Arabidopsis.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 86 citations in OpenAlex.
- A Structural Perspective on the RNA Editing of Plant Respiratory Complexes.International journal of molecular sciences · 2022Article
- Cotton Fiber Development Requires the Pentatricopeptide Repeat Protein GhIm for Splicing of Mitochondrial nad7 mRNA.Genetics · 2021Article
- The novel E-subgroup pentatricopeptide repeat protein DEK55 is responsible for RNA editing at multiple sites and for the splicing of nad1 and nad4 in maize.BMC plant biology · 2020Article
- Systematic analysis reveals cis and trans determinants affecting C-to-U RNA editing in Arabidopsis thaliana.BMC genetics · 2020Article
- Dynamic response of RNA editing to temperature in grape by RNA deep sequencing.Functional & integrative genomics · 2020Article
- Lose-of-Function of a Rice Nucleolus-Localized Pentatricopeptide Repeat Protein Is Responsible for the floury endosperm14 Mutant Phenotypes.Rice (New York, N.Y.) · 2019Article
- The chloroplast and mitochondrial C-to-U RNA editing inPlant direct · 2019Article
- Molecular and Functional Diversity of RNA Editing in Plant Mitochondria.Molecular biotechnology · 2018Review
- The Pentatricopeptide Repeat Gene Family inMolecules (Basel, Switzerland) · 2018Article
- Editing of Mitochondrial TranscriptsGenetics · 2017Article
- Mitochondrial Defects Confer Tolerance against Cellulose Deficiency.The Plant cell · 2016Article
- RNA Recognition Motif-Containing Protein ORRM4 Broadly Affects Mitochondrial RNA Editing and Impacts Plant Development and Flowering.Plant physiology · 2016Article
- Two pentatricopeptide repeat domain proteins are required for the synthesis of respiratory complex I.Current genetics · 2015Article
- Regulation of inflorescence branch development in rice through a novel pathway involving the pentatricopeptide repeat protein sped1-D.Genetics · 2014Article
- Mitochondrial RNA editing PPR proteins can tolerate protein tags at E as well as at DYW domain termini.Frontiers in plant science · 2014Article
- Empty pericarp5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize.The Plant cell · 2013Article
- MEF10 is required for RNA editing at nad2-842 in mitochondria of Arabidopsis thaliana and interacts with MORF8.Plant molecular biology · 2013Article
- The longest mitochondrial RNA editing PPR protein MEF12 in Arabidopsis thaliana requires the full-length E domain.RNA biology · 2013Article
- Systematic study of subcellular localization of Arabidopsis PPR proteins confirms a massive targeting to organelles.RNA biology · 2013Article
- Two related RNA-editing proteins target the same sites in mitochondria of Arabidopsis thaliana.The Journal of biological chemistry · 2012Article
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1 author at 1 institution in 1 country.
Funding
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Abstract
RNA editing in plants alters specific nucleotides from C to U in mRNAs in plastids and in mitochondria. I here characterize the nuclear gene MITOCHONDRIAL EDITING FACTOR9 (MEF9) that is required for RNA editing of the site nad7-200 in the nad7 mitochondrial mRNA in Arabidopsis (Arabidopsis thaliana). The MEF9 protein belongs to the E subfamily of pentatricopeptide repeat proteins and unlike the three previously identified mitochondrial editing factors MEF1 and MEF11 in Arabidopsis and OGR1 in rice (Oryza sativa) does not contain a DYW C-terminal domain. In addition, the E domain is incomplete, but seems to be functionally required, since one of the two independent EMS mutants encodes a MEF9 protein truncated by a stop codon at the beginning of the E domain. In both mutant plants premature stop codons in MEF9 inactivate RNA editing at site nad7-200. The homozygous mutant plants are viable and develop rather normally. The lack of RNA editing at site nad7-200 thus seems to be tolerated although this editing event is conserved in most plant species or the genomic sequence already codes for a T at this position, resulting in a generally conserved amino acid codon.
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