ArticlePlant physiology2010
Stimulation of nonselective amino acid export by glutamine dumper proteins.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 89 citations in OpenAlex.
- Calcium and Nitrogen Availability Controls Root Exudation in Hydroponically Cultured Barley.Plant, cell & environment · 2026Article
- The Arabidopsis neutral amino acid transporter UmamiT20 confers Botrytis cinerea susceptibility.Journal of experimental botany · 2026Article
- Glutamine alleviates the toxicity of externally applied amino acids in Arabidopsis.Frontiers in plant science · 2026Article
- Comparative Genomics of Viral Genomes and Identification of Three Novel Viroporin-Like Superfamilies.Microbial physiology · 2026Article
- Root Exudates in Soilless Culture Conditions.Plants (Basel, Switzerland) · 2025Review
- Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.Frontiers in microbiology · 2025Article
- The Genetic Dissection of Nitrogen Use-Related Traits in Flax (International journal of molecular sciences · 2023Article
- Rhizobial nitrogen fixation efficiency shapes endosphere bacterial communities and Medicago truncatula host growth.Microbiome · 2023Article
- Arabidopsis ACT DOMAIN REPEAT9 represses glucose signaling pathways.Plant physiology · 2023Article
- Elicitor-induced plant immunity relies on amino acids accumulation to delay the onset of bacterial virulence.Plant physiology · 2023Article
- Novel candidate genes for lignin structure identified through genome-wide association study of naturally varyingFrontiers in plant science · 2023Article
- A spatiotemporal transcriptomic network dynamically modulates stalk development in maize.Plant biotechnology journal · 2022Article
- Review
- MAMP-elicited changes in amino acid transport activity contribute to restricting bacterial growth.Plant physiology · 2022Article
- Cellular export of sugars and amino acids: role in feeding other cells and organisms.Plant physiology · 2021Review
- Defective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- The Transcription Factor EIL1 Participates in the Regulation of Sulfur-Deficiency Response.Plant physiology · 2020Article
- Amino Acid Transporters in Plants: Identification and Function.Plants (Basel, Switzerland) · 2020Review
- Increased Expression of UMAMIT Amino Acid Transporters Results in Activation of Salicylic Acid Dependent Stress Response.Frontiers in plant science · 2020Article
- Intrusive Growth of Phloem Fibers in Flax Stem: Integrated Analysis of miRNA and mRNA Expression Profiles.Plants (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phloem and xylem transport of amino acids involves two steps: export from one cell type to the apoplasm, and subsequent import into adjacent cells. High-affinity import is mediated by proton/amino acid cotransporters, while the mechanism of export remains unclear. Enhanced expression of the plant-specific type I membrane protein Glutamine Dumper1 (GDU1) has previously been shown to induce the secretion of glutamine from hydathodes and increased amino acid content in leaf apoplasm and xylem sap. In this work, tolerance to low concentrations of amino acids and transport analyses using radiolabeled amino acids demonstrate that net amino acid uptake is reduced in the glutamine-secreting GDU1 overexpressor gdu1-1D. The net uptake rate of phenylalanine decreased over time, and amino acid net efflux was increased in gdu1-1D compared with the wild type, indicating increased amino acid export from cells. Independence of the export from proton gradients and ATP suggests that overexpression of GDU1 affects a passive export system. Each of the seven Arabidopsis (Arabidopsis thaliana) GDU genes led to similar phenotypes, including increased efflux of a wide spectrum of amino acids. Differences in expression profiles and functional properties suggested that the GDU genes fulfill different roles in roots, vasculature, and reproductive organs. Taken together, the GDUs appear to stimulate amino acid export by activating nonselective amino acid facilitators.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.