ArticleDrug and alcohol dependence2010
A new definition of early age at onset in alcohol dependence.
Article in Drug and alcohol dependence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- BDNF Haplotype and Personality Traits May Influence the Development of Alcohol Use Disorder in the Han Chinese Population.Addiction biology · 2025Article
- Characterizing midlife-onset alcohol dependence: Implications for etiology, prevention, and healthy aging.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- The association betweenNeuropsychiatric disease and treatment · 2019Article
- The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings.Social psychiatry and psychiatric epidemiology · 2015Review
- Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Drug and alcohol dependence · 2014Article
- Cognitive mediators and disparities in the relation between teen depressiveness and smoking.Drug and alcohol dependence · 2014Article
- Effects of Δ9-tetrahydrocannabinol in individuals with a familial vulnerability to alcoholism.Psychopharmacology · 2014Article
- "Queasy does it": false alcohol beliefs and memories may lead to diminished alcohol preferences.Acta psychologica · 2013Article
- Age of alcohol and cannabis use onset mediates the association of transmissible risk in childhood and development of alcohol and cannabis disorders: evidence for common liability.Experimental and clinical psychopharmacology · 2013Article
- Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.Journal of studies on alcohol and drugs · 2011Article
- Psychosocial profile of male perpetrators of domestic violence: A population-based study.Industrial psychiatry journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveThe accurate cut-off of an early onset of alcohol dependence is unknown. The objectives of this analysis are (1) to confirm that ages at onset variability in alcohol dependence is best described as a two subgroups entity, (2) to define the most appropriate cut-off, and (3) to test the relevancy of such distinction.
methodData were drawn the Epidemiologic Survey on Alcohol and Related Conditions (NESARC). This study focused on the 4782 adults with lifetime alcohol dependence.
resultsThe best-fit model distinguished two subgroups of age at onset of alcohol dependence, with a cut-off point at 22 years. Subjects with an earlier onset of alcohol dependence (< or = 22 years old) reported higher lifetime rates of specific phobia, antisocial behaviors and nearly all addictive disorders.
conclusionsThe early onset of alcohol dependence is best defined as beginning before the age of 22 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.