ArticleNeurobiology of aging2011
Age-related deficits in a forebrain-dependent task, trace-eyeblink conditioning.
Article in Neurobiology of aging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Article
- Aging-Related Alterations to Persistent Firing in the Lateral Entorhinal Cortex Contribute to Deficits in Temporal Associative Memory.Frontiers in aging neuroscience · 2022Review
- Article
- Age-related differences in appetitive trace conditioning and novel object recognition procedures.Neurobiology of learning and memory · 2019Article
- Potentiation rather than distraction in a trace fear conditioning procedure.Behavioural processes · 2016Article
- Spine loss in primary somatosensory cortex during trace eyeblink conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Ro 04-6790-induced cognitive enhancement: no effect in trace conditioning and novel object recognition procedures in adult male Wistar rats.Pharmacology, biochemistry, and behavior · 2014Article
- Training-dependent associative learning induced neocortical structural plasticity: a trace eyeblink conditioning analysis.PloS one · 2014Article
- Aging in the cerebellum and hippocampus and associated behaviors over the adult life span of CB6F1 mice.Neuroscience · 2013Article
- Amygdala's involvement in facilitating associative learning-induced plasticity: a promiscuous role for the amygdala in memory acquisition.Frontiers in integrative neuroscience · 2012Article
- Characterizing cognitive aging of associative memory in animal models.Frontiers in aging neuroscience · 2012Article
- Reevaluating hippocampus-dependent learning in FVB/N mice.Behavioral neuroscience · 2011Article
- Physiological and anatomical studies of associative learning: Convergence with learning studies of W.T. Greenough.Developmental psychobiology · 2011Review
Corrections and comments
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3 authors.
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Abstract
Trace-eyeblink conditioning is a forebrain-dependent learning paradigm that has assisted in our understanding of age-related hippocampal neuronal plasticity; however, the hippocampus is not believed to be the permanent site for most long-term-memory storage. Studies in adult subjects have suggested the neocortex as one such site. Whisker plucking studies have further suggested that the ability for plasticity in the neocortex declines with age. Mice were trained in trace- and delay-eyeblink conditioning with whisker or auditory stimulation as the conditioned stimulus to examine possible age-related behavioral and neocortical abnormalities. Whisker stimulation was determined to be a more effective stimulus for examining age-related behavioral abnormalities in C57 mice. Additionally, neocortical barrel expansion, observed in trace conditioned adult mice and rabbits, does not occur in mice conditioned on a delay paradigm or in old mice unable to learn the whisker trace association. Abnormalities in neocortical memory storage in the elderly could contribute to normal age-dependent declines in associative learning abilities.
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