Evidence map›Paper›PMID 20018097›Full record

ReviewBMC musculoskeletal disorders2009

Malformations of the craniocervical junction (Chiari type I and syringomyelia: classification, diagnosis and treatment).

Alfredo Avellaneda Fernández, Alberto Isla Guerrero, Maravillas Izquierdo Martínez, María Eugenia Amado Vázquez, Javier Barrón Fernández, Ester Chesa i Octavio, Javier De la Cruz Labrado, Mercedes Escribano Silva, Marta Fernández de Gamboa Fernández de Araoz, Rocío García-Ramos and 5 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in BMC musculoskeletal disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02669836 (Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02669836 nacompletednot on this mapstarted 2016, after this paper: background citation

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

TypeinterventionalSponsorWashington University School of MedicineRan2016 to 2020Enrolled162ConditionsArnold-Chiari Malformation, Type 1, Chiari Malformation Type I, Type I Arnold-Chiari Malformation, SyringomyeliaArmsPosterior fossa decompression, Dural Augmentation
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 262 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Alfredo Avellaneda FernándezCarlos III Health Institute, Sinesio Delgado n. 6 (pavilion 12), 28029 Madrid, Spain. alfavel@gmail.com
Alberto Isla Guerrero
Maravillas Izquierdo Martínez
María Eugenia Amado Vázquez
Javier Barrón Fernández
Ester Chesa i Octavio
Javier De la Cruz Labrado
Mercedes Escribano Silva
Marta Fernández de Gamboa Fernández de Araoz
Rocío García-Ramos
Miguel García Ribes
Carmen Gómez
Joaquín Insausti Valdivia
Ramón Navarro Valbuena
José R Ramón
Spanish Society of Family and Community Medicine · ESInstituto de Salud Carlos III · ESSpanish Society of Hematology and Hemotherapy · ESUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiari disease (or malformation) is in general a congenital condition characterized by an anatomic defect of the base of the skull, in which the cerebellum and brain stem herniate through the foramen magnum into the cervical spinal canal. The onset of Chiari syndrome symptoms usually occurs in the second or third decade (age 25 to 45 years). Symptoms may vary between periods of exacerbation and remission. The diagnosis of Chiari type I malformation in patients with or without symptoms is established with neuroimaging techniques. The most effective therapy for patients with Chiari type I malformation/syringomyelia is surgical decompression of the foramen magnum, however there are non-surgical therapy to relieve neuropathic pain: either pharmacological and non-pharmacological. Pharmacological therapy use drugs that act on different components of pain. Non-pharmacological therapies are primarily based on spinal or peripheral electrical stimulation. It is important to determine the needs of the patients in terms of health-care, social, educational, occupational, and relationship issues, in addition to those derived from information aspects, particularly at onset of symptoms. Currently, there is no consensus among the specialists regarding the etiology of the disease or how to approach, monitor, follow-up, and treat the condition. It is necessary that the physicians involved in the care of people with this condition comprehensively approach the management and follow-up of the patients, and that they organize interdisciplinary teams including all the professionals that can help to increase the quality of life of patients.

Indexed as

Arnold-Chiari MalformationHumansSyringomyelia

Identifiers

PMID20018097
PMCPMC2796052
OpenAlexW2031215651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.