ArticleBMC proceedings2009
Contrasting identity-by-descent estimators, association studies, and linkage analyses using the Framingham Heart Study data.
Article in BMC proceedings, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Cryptic relatedness in epidemiologic collections accessed for genetic association studies: experiences from the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) study and the National Health and Nutrition Examination Surveys (NHANES).Frontiers in genetics · 2015Article
- Genome scan for spelling deficits: effects of verbal IQ on models of transmission and trait gene localization.Behavior genetics · 2011Article
- Estimation and visualization of identity-by-descent within pedigrees simplifies interpretation of complex trait analysis.Human heredity · 2011Article
- Combining information from linkage and association methods.Genetic epidemiology · 2009Article
- Conditional tests for localizing trait genes.Human heredity · 2009Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
We explored the utility of population- and pedigree-based analyses using the Framingham Heart Study genome-wide 50 k single-nucleotide polymorphism marker data provided for Genetic Analysis Workshop 16. Our aims were: 1) to compare identity-by-descent sharing estimates from variable amounts of data; 2) to apply each of these estimates to a case-control association study designed to control for relatedness among samples; and 3) to contrast these results to those obtained using model-based and model-free linkage analysis methods.
Identifiers
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Registered trials
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