Evidence map›Paper›PMID 2001716›Full record

ReviewExperientia1991

Molecular parasitology: progress towards the development of vaccines for malaria, filariasis, and schistosomiasis.

S J Cryz

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Experientia, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

S J CryzSwiss Serum and Vaccine Institute, Bern.
Swiss Vaccine Research Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in molecular biology have allowed for the identification of potential vaccine candidates against several parasitic diseases. Antigens from various life stages of Plasmodium and Schistosoma species and filarial worms have been cloned, sequenced and tested as vaccines. Results to date in animal models have been promising. Modest levels of protection against experimental human malaria have been obtained using both sporozoite and blood-stage antigens. However, a greater understanding of the mechanisms which lead to immunity against parasites is required before effective vaccines can be developed.

Indexed as

Amino Acid SequenceAnimalsAntigens, HelminthAntigens, ProtozoanFilariasisHumansImmunity, CellularMalariaMolecular Sequence DataPlasmodium falciparumSchistosomiasisVaccinationVaccines, SyntheticAntigens, HelminthAntigens, ProtozoanVaccines, Synthetic

Identifiers

PMID2001716
OpenAlexW1965964271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.