ReviewExperientia1991
mRNA processing in the Trypanosomatidae.
Review in Experientia, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Molecular aspects of cyclophilins mediating therapeutic actions of their ligands.Cellular and molecular life sciences : CMLS · 2010Review
- Searching the Tritryp genomes for drug targets.Advances in experimental medicine and biology · 2008Review
- Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation.Molecular and biochemical parasitology · 2007Article
- Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene.Nucleic acids research · 2003Article
- Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites.Molecular and cellular biology · 2000Article
- Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- A common core structure for U3 small nucleolar RNAs.Nucleic acids research · 1994Article
- Kinetics of an RNA conformational switch.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Molecular organization of Leishmania RNA virus 1.Proceedings of the National Academy of Sciences of the United States of America · 1992Article
- High-efficiency clonal growth of bloodstream- and insect-form Trypanosoma brucei on agarose plates.Proceedings of the National Academy of Sciences of the United States of America · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Members of the Trypanosomatidae, which include the African trypanosomes, the American trypanosomes and the leishmanias, cause disease in vast proportions in man and his livestock and are a major detrimental factor to the social and economic well-being of the third world. Current research using the techniques of molecular biology has revealed two unusual types of mRNA processing in these protozoans; these are the addition of a shared leader sequence to the 5' ends of nuclear mRNAs by a mechanism of trans splicing, and the insertion and deletion of specific uridine residues in mitochondrial transcripts by RNA editing. The presence of these two mRNA processing pathways in the Trypanosomatidae has profound consequences for the organization and expression of their genetic information.
Indexed as
Identifiers
2001714What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.