Evidence map›Paper›PMID 20017133›Full record

ArticleHuman brain mapping2010

The SRI24 multichannel atlas of normal adult human brain structure.

Torsten Rohlfing, Natalie M Zahr, Edith V Sullivan, Adolf Pfefferbaum

Abstract readComparative Study
In one paragraph

Article in Human brain mapping, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 272 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
272citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

272 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Integrating Anatomical Priors Into a Causal Diffusion Model.IEEE transactions on medical imaging · 2026
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212 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Torsten RohlfingSRI International, Neuroscience Program, Menlo Park, California 94025-3493, USA. torsten@synapse.sri.com
Natalie M Zahr
Edith V Sullivan
Adolf Pfefferbaum

Funding

TRACKING HIV INFECTION AND ALCOHOL ABUSE CNS COMORBIDITY WITH NEUROIMAGINGU01AA017347 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, SULLIVAN, EDITH VIONI · 2007 to 2021
$16.0M
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR01AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF, ZAHR, NATALIE M · 1985 to 2025
$13.0M
Cerebellar Structure and Function in AlcoholismR37AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2010 to 2019
$5.4M
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingR01AA017347 · NIAAA · SRI INTERNATIONAL · PI Adolf Pfefferbaum · 2022 to 2026
$5.2M
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR37AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF · 1996 to 2005
$4.4M
NORMAL AGING OF BRAIN STRUCTURE AND FUNCTIONR01AG017919 · NIA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2000 to 2010
$3.9M
Translational Studies of Brain Circuitry Disrupted by AlcoholismK05AA017168 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2008 to 2017
$2.2M
Continued Development and Maintenance of a Computational Morphometry ToolkitR01EB008381 · NIBIB · SRI INTERNATIONAL · PI ROHLFING, TORSTEN · 2009 to 2010
$249k
NIAAA NIH HHS AA005965NIAAA NIH HHS AA012888NIAAA NIH HHS AA017168NIAAA NIH HHS AA017347NIAAA NIH HHS K05 AA017168NIAAA NIH HHS R01 AA005965NIAAA NIH HHS R01 AA017347NIAAA NIH HHS R37 AA005965NIAAA NIH HHS R37 AA010723NIAAA NIH HHS U01 AA017347NIA NIH HHS AG017919NIA NIH HHS R01 AG017919NIBIB NIH HHS EB008381NIBIB NIH HHS R01 EB008381
6 · The paper itself

Abstract

This article describes the SRI24 atlas, a new standard reference system of normal human brain anatomy, that was created using template-free population registration of high-resolution magnetic resonance images acquired at 3T in a group of 24 normal control subjects. The atlas comprises anatomical channels (T1, T2, and proton density weighted), diffusion-related channels (fractional anisotropy, mean diffusivity, longitudinal diffusivity, mean diffusion-weighted image), tissue channels (CSF probability, gray matter probability, white matter probability, tissue labels), and two cortical parcellation maps. The SRI24 atlas enables multichannel atlas-to-subject image registration. It is uniquely versatile in that it is equally suited for the two fundamentally different atlas applications: label propagation and spatial normalization. Label propagation, herein demonstrated using diffusion tensor image fiber tracking, is enabled by the increased sharpness of the SRI24 atlas compared with other available atlases. Spatial normalization, herein demonstrated using data from a young-old group comparison study, is enabled by its unbiased average population shape property. For both propagation and normalization, we also report the results of quantitative comparisons with seven other published atlases: Colin27, MNI152, ICBM452 (warp5 and air12), and LPBA40 (SPM5, FLIRT, AIR). Our results suggest that the SRI24 atlas, although based on 3T MR data, allows equally accurate spatial normalization of data acquired at 1.5T as the comparison atlases, all of which are based on 1.5T data. Furthermore, the SRI24 atlas is as suitable for label propagation as the comparison atlases and detailed enough to allow delineation of anatomical structures for this purpose directly in the atlas.

Indexed as

Atlases as TopicAccess to InformationAdultAgedAged, 80 and overAgingAlgorithmsBrainDiffusion Magnetic Resonance ImagingFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalInternetMagnetic Resonance ImagingMale

Identifiers

PMID20017133
PMCPMC2915788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.