ArticleThe open cardiovascular medicine journal2009
Initiation and persistence to statin treatment in patients with diabetes receiving glucose-lowering medications 1997- 2006.
Article in The open cardiovascular medicine journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Multiple Socioeconomic Circumstances and Initiation of Cardiovascular Medication among Ageing Employees.International journal of environmental research and public health · 2021Article
- Income differences in the type of antihypertensive medicines used in ambulatory settings in Finland: a register-based study.European journal of clinical pharmacology · 2015Article
- Are statin trials in diabetes representative of real-world diabetes care: a population-based study on statin initiators in Finland.BMJ open · 2014Article
- Monitoring the use of lipid-lowering medication among persons with newly diagnosed diabetes: a nationwide register-based study.BMJ open · 2013Article
- Do immigrants from Turkey, Pakistan and Ex-Yugoslavia with newly diagnosed type 2 diabetes initiate recommended statin therapy to the same extent as Danish-born residents? A nationwide register study.European journal of clinical pharmacology · 2013Article
- Is the high-risk strategy to prevent cardiovascular disease equitable? A pharmacoepidemiological cohort study.BMC public health · 2012Article
- Article
- Changes in short- and long-term cardiovascular risk of incident diabetes and incident myocardial infarction--a nationwide study.Diabetologia · 2010Article
- National Background is Associated with Disparities in Initiation and Persistence to Statin Treatment in Subjects with Diabetes in Denmark.Frontiers in pharmacology · 2010Article
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10 authors.
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Abstract
aimsSince 2001 guidelines recommend statin treatment in most patients with diabetes. We investigated secular changes in initiation and persistence to statin treatment during a 10-year period in a nationwide cohort of patients initiating glucose-lowering medication (GLM).
methodsAll Danish citizens 30 years and older who claimed prescriptions of GLM between 1997 and 2006 were identified from nationwide registers of drug dispensing from pharmacies and hospitalizations, and followed until 2006. Statin treatment was registered if a prescription was claimed during the period. By logistic regression we analyzed factors related to initiation and persistence to statin treatment.
resultsIn total 128,106 patients were included. In 1997 only 7% of the patients receiving GLM claimed statins within the first year after GLM initiation. Despite increasing statin prescriptions the following years, only 62% were using statins at the end of follow up. The chance of ever receiving statins was lowest if not initiated within 180-days following the first purchase of GLM (OR 0.75, 95% CI 0.74-0.76). A previous myocardial infarction was associated with increased statin treatment (OR 4.51; 95% CI 4.31 - 4.71), while low income was associated with lower use of statins (OR 0.68; 95%CI 0.66-0.72). Between 75-85 % of the patients who initiated statins treatment were persistent to treatment by 2007.
conclusionsIn spite of increasing use of statins in diabetes patients over time, many patients remain untreated. Early initiation of statin treatment in diabetic patients and focus on patients with low socioeconomic status is needed to give long-term benefits.
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