Evidence map›Paper›PMID 20016524›Full record

ArticleJournal of human hypertension2010

Mid-life blood pressure levels and the 8-year incidence of type 2 diabetes mellitus: the Rancho Bernardo Study.

C K Kramer, D von Mühlen, E Barrett-Connor

Open access · bronzeAbstract read
In one paragraph

Article in Journal of human hypertension, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Insulin Resistance the Hinge Between Hypertension and Type 2 Diabetes.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Evaluation of the National Kidney Foundation of Hawai'i's Kidney Early Detection Screening program.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2012
    Article
  11. Article
  12. Article
  13. Diabetic heart disease: the story continues.Journal of human hypertension · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C K KramerDivision of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0607, USA.
D von Mühlen
E Barrett-Connor
University of California, San Diego · US

Funding

STUDY OF RISK FACTORS FOR OSTEOPOROSIS IN THE ELDERLYR37AG007181 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1987 to 2010
$5.4M
GENDER DIFFERENCES IN OSTEOPOROSISR01AG007181 · NIA · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1999 to 2002
$1.6M
CVD Predictors of Cognitive Function Trajectory over 20 YearsR01AG028507 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 2007 to 2010
$1.2M
EPIDEMIOLOGY OF NIDDM AND IGT IN AN ADULT COMMUNITYR01DK031801 · NIDDK · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1986 to 2000
$606k
NIA NIH HHS AG028507NIA NIH HHS AG07181NIA NIH HHS R01 AG007181NIA NIH HHS R01 AG028507NIA NIH HHS R37 AG007181NIDDK NIH HHS R01 DK031801
6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) and hypertension frequently occur together. We examined whether blood pressure (BP) levels predict 8-year incident diabetes. Participants were community-dwelling older adults who had BP measured twice and an oral glucose tolerance test at baseline and again 8.3 years later. At baseline, participants were classified as normotensive (systolic blood pressure (SBP) <120 mm Hg and diastolic blood pressure (DBP) <80 mm Hg; n=242); prehypertensive (SBP>or=120 and <140 mm Hg or DBP>or=80 and <90 mm Hg; n=426); or hypertensive (SBP>or=140 mm Hg or DBP>or=90 mm Hg or using anti-hypertensive medication; n=457). There were 1125 participants (mean age 66.0 years; 44.3% men) who attended the baseline and follow-up visit, of whom 85 had new onset T2DM. Participants who developed T2DM had higher mean body mass index (BMI) and BP levels than those who did not develop diabetes. In logistic regression models adjusted for age, sex, BMI, and physical activity, the odds of incident T2DM was greater in prehypertensives (odds ratio (OR) 2.32 95% confidence interval (CI) 1.05-5.1, P=0.03) and hypertensives (OR 3.5 95% CI 1.50-8.0, P=0.002) compared with normotensives. Excluding participants who used anti-hypertensive medications did not change results. In conclusion, mid-life hypertension and prehypertension predicted future diabetes, independent of BMI. Glucose surveillance should be encouraged in adults with prehypertension or hypertension.

Indexed as

Blood PressureAgedAge DistributionBody Mass IndexCaliforniaDiabetes Mellitus, Type 2FemaleHumansHypertensionIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisObesityPredictive Value of Tests

Identifiers

PMID20016524
PMCPMC2888977
OpenAlexW2026625389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.