ArticleBMC evolutionary biology2009
Molecular evolution of sex-biased genes in the Drosophila ananassae subgroup.
Article in BMC evolutionary biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Recombination Suppression Drives Expansion of the Drosophila Dot Chromosome.Molecular biology and evolution · 2025Article
- Molecular population genetics of Sex-lethal (Sxl) in the Drosophila melanogaster species group: a locus that genetically interacts with Wolbachia pipientis in Drosophila melanogaster.G3 (Bethesda, Md.) · 2021Article
- Article
- Transcriptome Analysis Reveals Candidate Genes for Cold Tolerance in Drosophila ananassae.Genes · 2018Article
- Genetic constraints on microevolutionary divergence of sex-biased gene expression.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Biased Inference of Selection Due to GC-Biased Gene Conversion and the Rate of Protein Evolution in Flycatchers When Accounting for It.Molecular biology and evolution · 2018Article
- Mating Changes Sexually Dimorphic Gene Expression in the Seed Beetle Callosobruchus maculatus.Genome biology and evolution · 2017Article
- Recent and Long-Term Selection Across Synonymous Sites in Drosophila ananassae.Journal of molecular evolution · 2016Article
- The coevolutionary period of Wolbachia pipientis infecting Drosophila ananassae and its impact on the evolution of the host germline stem cell regulating genes.Molecular biology and evolution · 2014Article
- Positive selection in nucleoporins challenges constraints on early expressed genes in Drosophila development.Genome biology and evolution · 2013Article
- The evolution of gene expression and the transcriptome-phenotype relationship.Seminars in cell & developmental biology · 2012Review
- Rate of amino acid substitution is influenced by the degree and conservation of male-biased transcription over 50 myr of Drosophila evolution.Genome biology and evolution · 2012Article
- Inter- and intraspecific variation in Drosophila genes with sex-biased expression.International journal of evolutionary biology · 2012Article
- Weighing the evidence for adaptation at the molecular level.Trends in genetics : TIG · 2011Article
- Article
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3 authors.
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Abstract
backgroundGenes with sex-biased expression often show rapid molecular evolution between species. Previous population genetic and comparative genomic studies of Drosophila melanogaster and D. simulans revealed that male-biased genes have especially high rates of adaptive evolution. To test if this is also the case for other lineages within the melanogaster group, we investigated gene expression in D. ananassae, a species that occurs in structured populations in tropical and subtropical regions. We used custom-made microarrays and published microarray data to characterize the sex-biased expression of 129 D. ananassae genes whose D. melanogaster orthologs had been classified previously as male-biased, female-biased, or unbiased in their expression and had been studied extensively at the population-genetic level. For 43 of these genes we surveyed DNA sequence polymorphism in a natural population of D. ananassae and determined divergence to the sister species D. atripex and D. phaeopleura.
resultsSex-biased expression is generally conserved between D. melanogaster and D. ananassae, with the majority of genes exhibiting the same bias in the two species. However, about one-third of the genes have either gained or lost sex-biased expression in one of the species and a small proportion of genes (approximately 4%) have changed bias from one sex to the other. The male-biased genes of D. ananassae show evidence of positive selection acting at the protein level. However, the signal of adaptive protein evolution for male-biased genes is not as strong in D. ananassae as it is in D. melanogaster and is limited to genes with conserved male-biased expression in both species. Within D. ananassae, a significant signal of adaptive evolution is also detected for female-biased and unbiased genes.
conclusionsOur findings extend previous observations of widespread adaptive protein evolution to an independent Drosophila lineage, the D. ananassae subgroup. However, the rate of adaptive evolution is not greater for male-biased genes than for female-biased or unbiased genes, which suggests that there are differences in sex-biased gene evolution between the two lineages.
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