Evidence map›Paper›PMID 20014865›Full record

ReviewACS chemical biology2010

Making the cut: the chemical biology of cytokinesis.

G Ekin Atilla-Gokcumen, Adam B Castoreno, Sofia Sasse, Ulrike S Eggert

Open access · greenAbstract readReview
In one paragraph

Review in ACS chemical biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Membrane and organelle dynamics during cell division.Nature reviews. Molecular cell biology · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Capping protein regulates actin dynamics during cytokinetic midbody maturation.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

G Ekin Atilla-GokcumenDana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Adam B Castoreno
Sofia Sasse
Ulrike S Eggert
Harvard University · USDana-Farber Cancer Institute · US

Funding

Small molecule probes of cytokinesisR01GM082834 · NIGMS · DANA-FARBER CANCER INST · PI EGGERT, ULRIKE S · 2008 to 2012
$2.6M
NIGMS NIH HHS R01 GM082834
6 · The paper itself

Abstract

Cytokinesis is the last step in the cell cycle, where daughter cells finally separate. It is precisely regulated in both time and space to ensure that each daughter cell receives an equal share of DNA and other cellular materials. Chemical biology approaches have been used very successfully to study the mechanism of cytokinesis. In this review, we discuss the use of small molecule probes to perturb cytokinesis, as well as the role naturally occurring small molecule metabolites such as lipids play during cytokinesis.

Indexed as

Signal TransductionAnimalsCytokinesisHumans

Identifiers

PMID20014865
PMCPMC2807474
OpenAlexW2036206684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.