Evidence map›Paper›PMID 20013071›Full record

ArticleObesity surgery2010

Manometric changes of the lower esophageal sphincter after sleeve gastrectomy in obese patients.

Italo Braghetto, Enrique Lanzarini, Owen Korn, Héctor Valladares, Juan Carlos Molina, Ana Henriquez

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 119 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 7 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02144545 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Study of Impact of the Size of Gastric Sleeve o the Weight Loss in Patients Submitted to Bariatric Surgery. Evaluation of Changes in Gastric Motility and Endocrine-metabolic Function.

TypeinterventionalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2013 to 2017Enrolled100ConditionsObesity, MorbidArmsBougie Size 33 Fr, Bougie Size 42 Fr, Distance pylorus 2 cm, Distance pylorus 5 cm
NCT03776669 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients: a Single-center Randomized Controlled Trial

TypeinterventionalSponsorNational Taiwan University HospitalRan2019 to 2024Enrolled70ConditionsMorbid Obesity, Hiatal Hernia, Gastroesophageal Reflux Disease, Sleeve GastrectomyArmsLaparoscopic sleeve gastrectomy + Hiatal hernia repair, Laparoscopic sleeve gastrectomy alone
3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 7 syntheses or guidelines pooled it, 278 citations in OpenAlex.

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  20. Associations of Metabolically Healthy Obesity with Gastroesophageal Reflux Disease and Ineffective Esophageal Motility.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Italo BraghettoDepartment of Surgery, Faculty of Medicine, University of Chile, Santos Dumont 999, Santiago, Chile. ibraghet@redclinicauchile.cl
Enrique Lanzarini
Owen Korn
Héctor Valladares
Juan Carlos Molina
Ana Henriquez
University of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLaparoscopic sleeve gastrectomy has been accepted as an option for surgical treatment of obesity. After surgery, some patients present reflux symptoms associated with endoscopic esophagitis, therefore PPI's treatment must be indicated. PURPOSE: This study aims to evaluate the manometric characteristic of the lower esophageal sphincter (LES) before and after sleeve gastrectomy MATERIAL AND

methodThis prospective study includes 20 patients submitted to esophageal manometry in order to determine the resting pressure, and total and abdominal LES length before and after the sleeve gastrectomy. Statistical variations on the LESP were validated according to Student's "t" test.

resultsSeventeen female and three male patients were included, with a mean age of 37.6 +/- 12.6 years. All patients reduced their body weight, from an initial BMI of 38.3 kg/m(2) to 28.2 kg/m(2) 6 months after surgery. No postoperative complications were observed in these patients. Preoperative mean LESP was 14.2 +/- 5.8 mmHg. Postoperative manometry decreased in 17/20 (85%), with a mean value of 11.2 +/- 5.7 mmHg (p = 0.01). Seven of them presented LESP <12 mmHg and ten patients <6 mmHg after the operation. Furthermore, the abdominal length and total length of the high pressure zone at the esophagogastric junction were affected.

conclusionA sleeve gastrectomy produces an important decrease in LES pressure, which can in turn cause the appearance of reflux symptoms and esophagitis after the operation due to a partial resection of the sling fibers during the gastrectomy.

Indexed as

AdultBody Mass IndexEsophageal pH MonitoringEsophageal Sphincter, LowerEsophagitisEsophagogastric JunctionEsophagoscopyFemaleGastrectomyGastroesophageal RefluxHumansLaparoscopyMaleManometryObesityProspective StudiesProton Pump Inhibitors

Identifiers

PMID20013071
OpenAlexW1983948977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.